天津医药 ›› 2018, Vol. 46 ›› Issue (9): 992-994.doi: 10.11958/20180953

• 临床研究 • 上一篇    下一篇

肺叶切除术后房颤发生的影响因素分析

周方,卢喜科,张逊   

  1. 天津市胸科医院胸外科(邮编300222)
  • 收稿日期:2018-06-19 修回日期:2018-07-16 出版日期:2018-09-15 发布日期:2018-10-10
  • 通讯作者: 卢喜科 E-mail:luxike@yahoo.com

Analysis of the influencing factors of atrial fibrillation after pulmonary lobectomy

ZHOU Fang, LU Xi-ke, ZHANG Xun   

  1. Department of Thoracic Surgery, Tianjin Chest Hospital, Tianjin 300222, China
  • Received:2018-06-19 Revised:2018-07-16 Published:2018-09-15 Online:2018-10-10

摘要: 目的 分析肺叶切除术后房颤发生的影响因素。方法 回顾性分析2013年2月—2017年2月在本院328例行肺叶切除术患者的临床资料。根据肺叶切除术后是否发生房颤将患者分为房颤组(132例)和对照组(196例),对肺叶切除术后房颤发生的影响因素进行分析。结果 单因素分析显示,肺叶切除术后房颤的发生与患者年龄、性别、吸烟史、第一秒用力呼气量/用力肺活量(FEV1%)、术前肺部感染、术后氧分压等均有关(P<0.05);多因素Logistic回归分析结果显示,年龄>65岁、术前FEV1%<70%、术前肺部感染、术后氧分压<100 mmHg是肺叶切除术后发生房颤的危险因素。住院期间房颤组患者短期病死率、住院时间、住院费用均高于对照组,差异有统计学意义(P<0.05)。结论 肺叶切除术后房颤的危险因素较多,如高龄、术前肺部感染、FEV1%下降、术后氧分压低等,临床上需要加强对这些因素的预防,以降低术后房颤的发生率。

关键词: 肺切除术, 心房颤动, 危险因素

Abstract: Objective To analyze the influencing factors of atrial fibrillation after pulmonary lobectomy. Methods The clinical data of 328 patients with pulmonary lobectomy in our hospital from February 2013 to February 2017 were retrospectively analyzed. The patients were divided into atrial fibrillation group (132 cases) and control group (196 cases)according to whether atrial fibrillation occurred after pulmonary lobectomy, and the influencing factors of atrial fibrillation after pulmonary lobectomy were analyzed. Results The univariate factor analysis showed that the occurrence of atrial fibrillation after pulmonary lobectomy was related to the patient's age, gender, smoking history, preoperative forced expiratory volume in 1 second vs. forced vital capacity (FEV1%), preoperative lung infection, and postoperative oxygen partial pressure (P<0.05). Multivariate Logistic regression analysis showed that age > 65 years old, preoperative FEV1%<70%,preoperative lung infection and postoperative oxygen partial pressure<100 mmHg were the risk factors for atrial fibrillation after pulmonary lobectomy. The short-term mortality, length of hospital stay, and cost of stay during hospitalization were statistically significantly higher in the atrial fibrillator group than those in the control group (P<0.05).Conclusion There are many risk factors of atrial fibrillation after pulmonary lobectomy, such as age, pulmonary infection,drop of FEV1% and lower partial pressure of oxygen. These factors should be controlled in order to reduce the incidence of atrial fibrillation after pulmonary lobectomy.

Key words: pneumonectomy, atrial fibrillation, risk factors