天津医药 ›› 2020, Vol. 48 ›› Issue (2): 110-115.doi: 10.11958/20191484

• 临床研究 • 上一篇    下一篇

股骨开髓点外移对合并股骨外侧弓畸形的 全膝关节置换术的初步临床疗效

任志鹏 1,2,张福江 2,李桂石 3,康宇翔 2,赵荷珺 4,刘文彬 2,刘艳成 2,胡永成 2△   

  1. 1天津医科大学研究生院(邮编300070);2天津市天津医院骨科;3烟台毓璜顶医院关节外科;4天津市第一中心医院内分泌科
  • 收稿日期:2019-05-17 修回日期:2019-07-31 出版日期:2020-02-15 发布日期:2020-02-15
  • 通讯作者: 胡永成 E-mail:yongchenghu@126.com
  • 基金资助:
    GLP-1R信号通路调节NF-κBABCG2在胰腺癌化疗耐药中的作用及机制研究;胰高糖素样肽-1药物对胰腺癌的抑制作用及机制研究;组织特异性敲除Ihh基因治疗骨性关节炎的机制研究

Preliminary clinical effects of lateral femoral medullary opening position on total knee arthroplasty combined with lateral femoral arch deformity

REN Zhi-peng1,2, ZHANG Fu-jiang2, LI Gui-shi3, KANG Yu-xiang2, ZHAO He-jun4, LIU Wen-bin2, LIU Yan-cheng2, HU Yong-cheng2△   

  1. 1 Graduate School, Tianjin Medical University, Tianjin 300070, China; 2 Department of Orthopaedics, Tianjin Hospital; 3 Department of Joint Orthopaedics, Yantai Yuhuangding Hospital; 4 Department of Endocrinology, Tianjin First Central Hospital
  • Received:2019-05-17 Revised:2019-07-31 Published:2020-02-15 Online:2020-02-15

摘要: 摘要:目的 研究在合并股骨外侧弓畸形的全膝关节置换术(TKA)中外移股骨开髓位置对术后影像学及短期临 床疗效的影响。方法 选择2014年3月—2017年6月就诊于天津医院关节外科的合并股骨侧弓角超过3°的膝关节 炎患者40例(60膝),均行全膝关节表面置换术。其中2014年3月—2016年2月收治的28膝未做股骨开髓位置的调 整为标准位置开髓组(常规组),2016年3月—2017年6月收治的32膝股骨开髓位置较常规组水平外移5 mm,为开髓 位置外移组(设计组)。2组股骨截骨均采用髓内定位的方法,以固定6°作为股骨远端外翻截骨角。比较2组手术情 况、影像学及术后1年临床疗效的差异;影像学评价包括股骨外弓角、术前髋膝踝角、股骨外翻角、术后髋膝踝角、股 骨假体角、胫骨假体角、髌股关节对合角等,临床疗效评估包括术前、术后1年西安大略和麦克马斯特大学(WOMAC) 骨关节炎指数、膝关节协会评分(KSS)临床评分和Feller髌骨评分等。分别以180°±3°、90°±2°、90°±2°、≤10°作为术后 下肢力线、股骨假体位置、胫骨假体位置和髌股关节对合优良的标准。结果 2组手术均采用后交叉韧带保留型 (CR)膝关节假体,无1例发生内外侧副韧带损伤或止点断裂,术后切口均愈合良好。末次随访时2组均未发生感染、 假体松动、假体周围骨折等并发症。2组手术时间、股骨外弓角、术前髋膝踝角、股骨外翻角、术后胫骨假体角、术后 胫骨假体优良率、髌股关节对合优良率、术前WOMAC指数、KSS临床评分、Feller髌骨评分及术后1年WOMAC指数 差异均无统计学意义。但设计组术后髋膝踝角、股骨假体角、髌股对合角优于常规组(P<0.05),术后下肢力线和股 骨假体位置的优良率以及术后1年KSS临床评分、Feller髌骨评分均高于常规组(P<0.05)。结论 对于合并中重度 股骨外侧弓畸形的TKA病例,合理外移股骨开髓的位置,可以改善下肢力线、假体位置及髌股对合关系,短期随访临 床效果良好。

关键词: 骨关节炎, 膝, 关节成形术, 置换, 膝, 股骨畸形, 下肢力线, 机械轴

Abstract: Abstract: Objective To study the influence of outward-transferring the location of femoral medullary opening in Xray imaging and short-term clinical outcomes during total knee arthroplasty (TKA) with lateral femoral arch deformity. Methods Forty patients (60 knees) with knee arthropathy and with femoral lateral arch angle more than 3 degrees treated in Tianjin hospital from March 2014 to June 2017 were selected in this study. All patients were performed total knee arthroplasty. The cases were divided into two groups according to whether the position of femoral medullary opening was adjusted or not. Twenty-eight knees were in the standard position of femoral medullary opening group, referred to as the control group, and 32 knees were in the outward-transferring position group. The opening position was 5 mm horizontal outward shift than the standard position, referred to as the test group. In both groups, intramedullary osteotomy was performed. The fixation of 6 degrees was used as the angle of valgus osteotomy of distal femur. Statistical data of the two groups were collected to evaluate the operation situation and compare the difference of imaging and clinical effect between the two groups at 1 year after operation. The imaging evaluation included femoral lateral arch angle, preoperative hip-kneeankle angle, femoral valgus angle, postoperative hip-knee-ankle angle, femoral prosthesis angle, tibial prosthesis angle and patellofemoral congruent angle. Clinical efficacy evaluation included Western Ontario and McMaster Universities Osteoarthritis Index, Knee Society Score Clinical Score and Feller Patella Score before surgery and 1 year after operation. Then, 180°±3°, 90°±2°, 90°±2° and ≤10° were used as the criteria to evaluate the quality in the mechanical axis, femoral prosthesis position, tibial prosthesis position and patellofemoral joint. Results The baseline data of the two groups were consistent. All the operations were performed with Posterior Cruciate-Retaining (CR) knee prosthesis. No injury or rupture of medial or lateral collateral ligaments occurred. All operation time was less than 70 minutes, and the apparent bleeding volume was 10-20 mL. All incisions healed well after operation. At the last follow-up, no complications such as infection, prosthesis loosening and periprosthetic fracture were found in both groups. There were no significant differences in the duration of operation, femoral arch angle, preoperative hip-knee-ankle angle, femoral valgus angle, postoperative tibial prosthesis angle, postoperative tibial prosthesis excellent and good rate, patellofemoral joint excellent rate, preoperative WOMAC index, KSS clinical score, Feller patella score and 1 years postoperative WOMAC index between the two groups (P<0.05). However, the hip-knee-ankle angle, femoral prosthesis angle and patellofemoral angle were better in the test group than those in the control group (P<0.05). The excellence rate of mechanical axis and femoral prosthesis position in the external displacement group was better than that in the control group (P<0.05). KSS clinical score and Feller patella score were higher in the test group than those in control group at 1 year after surgey (P<0.05). Conclusion For TKA patients with moderate to severe lateral arch deformity of femur, reasonable displacement of femoral opening position can improve lower limb alignment, prosthesis position and patellofemoral joint relationship. The short-term follow-up has good clinical effect.

Key words: osteoarthritis, knee, arthroplasty, replacement, knee, femur deformity, limb alignment, mechanical axis