天津医药

天津医药 ›› 2018, Vol. 46 ›› Issue (3): 305-307.doi: 10.11958/20171018

• 临床研究 • 上一篇    下一篇

原发性喉、气管支气管淀粉样变一例

杨亚敏，李琦，张纳新   

  1. 天津市第三中心医院，天津市肝胆疾病研究所，天津市人工细胞重点实验室，卫生部人工细胞工程技术研究中心（邮编300170）
  • 收稿日期:2017-10-09 修回日期:2018-01-23 出版日期:2018-03-15 发布日期:2018-03-23
  • 通讯作者: 李琦 E-mail:yangyamin1977@yahoo.com

A case report of the primary laryngeal and tracheobronchial amyloidosis

YANG Ya-min, LI Qi, ZHANG Na-xin   

  1. The Third Central Hospital of Tianjin, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell,Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin 300170, China
  • Received:2017-10-09 Revised:2018-01-23 Published:2018-03-15 Online:2018-03-23

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摘要： 淀粉样变较少累及呼吸道，气管支气管淀粉样变较罕见，同时累及喉、气管及支气管的淀粉样变更为罕见。本文介绍 1 例喉、气管支气管淀粉样变的病例，该患者存在原发性喉淀粉样变，15 年后同时出现气管支气管淀粉样变。由于疾病罕见且临床表现不具特异性，导致患者曾被误诊为上呼吸道感染、支气管哮喘。患者经支气管镜镜下钳夹、氩气刀治疗后，症状明显缓解，目前病情较稳定，但仍需追踪远期预后。

关键词: 喉疾病, 气管, 支气管, 喉, 淀粉样变性

Abstract: Amyloidosis is less involved in the respiratory tract. The tracheobronchial amyloidosis is rare, and the amyloid changes involved in the larynx, trachea and bronchus are more rare. The study introduces a case of the primary laryngeal and tracheobronchial amyloidosis. The patient was diagnosed as primary laryngeal amyloidosis, and had tracheobronchial amyloidosis after 15 years. Due to the rare and non-specific clinical manifestations of the disease, the patient was misdiagnosed as upper respiratory tract infection and bronchial asthma. After the treatment of the clamp of the bronchoscope and argon knife，the symptoms were significantly relieved in the patient. At present, the disease is stable and has not relapsed, but it still needs to track the long-term prognosis.

Key words: laryngeal diseases, trachea, bronchi, larynx, amyloidosis