天津医药 ›› 2026, Vol. 54 ›› Issue (5): 544-549.doi: 10.11958/20253200

• 多学科诊疗 • 上一篇    下一篇

1例脓毒性心肌病继发心室电风暴患者多学科诊疗分析

李士欣(), 王佳佳, 何其瑾, 刘思琦, 姜潇思, 范习凯, 宋淑美, 翟建华()   

  1. 天津市人民医院南开大学第一附属医院老年医学科1(邮编 300121)
  • 收稿日期:2025-10-30 修回日期:2025-12-31 出版日期:2026-05-15 发布日期:2026-05-13
  • 通讯作者: E-mail:zhaijianhua@tmu.edu.cn
  • 作者简介:李士欣(1983),男,副主任医师,主要从事老年医学及超声临床应用方面研究。E-mail:smithwolf_06@sina.com.cn
  • 基金资助:
    天津市高等学校研究生教育改革研究计划项目(TJYG039)

Multidisciplinary diagnosis and treatment analysis of one case of ventricular electrical storm secondary to septic cardiomyopathy

LI Shixin(), WANG Jiajia, HE Qijin, LIU Siqi, JIANG Xiaosi, FAN Xikai, SONG Shumei, ZHAI Jianhua()   

  1. Department 1 of Geriatric Medicine, Tianjin Union Medical Center, the First Affiliated Hospital of Nankai University, Tianjin 300121, China
  • Received:2025-10-30 Revised:2025-12-31 Published:2026-05-15 Online:2026-05-13
  • Contact: E-mail:zhaijianhua@tmu.edu.cn

摘要:

心室电风暴(ES)是一种以短期内反复发生持续性室性心律失常为特征的心电不稳定状态,是交感风暴的心电表现,显著增加心源性猝死风险。ES多发生于结构性心脏病和遗传性心律失常患者,心力衰竭或容量过负荷、电解质紊乱、药物致心律失常是其常见诱因。脓毒症可继发交感神经过度兴奋、心肌功能及血流动力学障碍,诊疗中易出现容量过负荷,并可能需应用部分具有致心律失常作用药物,存在引发ES的病生理基础和促发因素。该文通过1例脓毒性心肌病继发ES患者的多学科诊疗过程,从老年医学、心血管病、药剂及重症医学不同学科出发,围绕患者发生ES的病生理基础、与基础疾病脓毒症的相关性、存在诱因、抗心律失常方案调整、心电生理干预措施选择及循环支持预案制定等方面进行总结分析,为临床医生准确识别ES原因、采取合理诊疗措施、提高ES救治成功率提供参考。

关键词: 心律失常, 心性, 心动过速, 室性, 脓毒症, 心肌疾病, 心室电风暴, 室性心律失常, 多学科诊疗

Abstract:

Ventricular electrical storm (ES) is a critical medical state defined by severe cardiac electrical instability, manifesting as repeated episodes of sustained ventricular arrhythmias within a short duration. As the cardiac expression of a sympathetic storm, ES significantly elevates the risk of sudden cardiac death. It predominantly occurs in patients with pre-existing structural heart disease or inherited arrhythmia syndromes. Precipitating factors frequently include heart failure, volume overload, electrolyte imbalance and drug-induced proarrhythmic effects. Sepsis can trigger exaggerated sympathetic tone, myocardial impairment and hemodynamic compromise. Clinical management of sepsis is frequently complicated by volume overload and may require the administration of medications with proarrhythmic potential. These elements collectively establish a pathophysiological environment that facilitates the emergence of ES. This article presents a case study of a patient with septic cardiomyopathy who developed ES. Through a multidisciplinary approach involving geriatrics, cardiology, pharmacy and critical care medicine, the study analyzes the pathophysiology of ES, its relationship between sepsis and ES, potential triggers, antiarrhythmic strategy adjustments, selection of electrophysiological interventions and planning of circulatory support. The findings aim to assist clinicians in accurately identifying the causes of ES, implementing appropriate treatment strategies and improving patient outcomes.

Key words: arrhythmias, cardiac, tachycardia, ventricular, sepsis, cardiomyopathies, electrical storm, ventricular arrhythmia, multi-disciplinary treatment

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