• 临床论丛 •    

紫龙金片联合化疗治疗大肠癌的临床观察

李桂,柴友龙   

  1. 天津市南开医院第四外科
  • 收稿日期:2013-07-12 修回日期:2013-08-03 出版日期:2013-10-15 发布日期:2013-10-15
  • 通讯作者: 李桂

Observation of colorectal advanced carcinoma s treated by combination of Zilongjin pieces and chemotherapy

chai you long2   

  • Received:2013-07-12 Revised:2013-08-03 Published:2013-10-15 Online:2013-10-15

摘要: 摘要:目的:观察紫龙金片联合由奥沙利铂(Oxaliplatin)、亚叶酸钙(CF)、氟尿嘧啶(5-Fu)组成的FOLFOX4方案及单用FOLFOX4方案化疗治疗大肠癌的疗效及不良反应。方法:45例接受化疗的大肠癌患者分为单用化疗组(对照组)及化疗并用紫龙金片组(治疗组)。结果:治疗组与对照组疗效评价比较,无统计学意义(p>0.05);KPS评分治疗组与对照组比较,差异有统计学意义(p<0.05);在骨髓抑制及恶心、呕吐副反应方面治疗组与对照组比较有统计学意义(P<0.05)。结论:紫龙金片联用FOLFOX4方案与单用FOLFOX4方案化疗治疗大肠癌相比能减轻化疗毒副作用,提高生活质量。

关键词: 结直肠肿瘤, 药物疗法, 联合, 生活质量, 紫龙金片

Abstract: 【Abstract】Objective:To observe the clinical effect of Zilongjin piece combined with chemotherapy in treatment of advanced colorectal carcinoma.Methods: Total of 45 patients were randomly divided into chemotherapy combined Zilongjin piece therapy group(treatment group,TG)and simple chemotherapy group(control group,CG).Results: TG and CG were compared in zhe efficacy ,there was no significant difference between the 2 group(P>0.05);KPS score of TG and CG were statistically significant difference (p