天津医药

• 临床论丛 •    

紫龙金片联合化疗治疗大肠癌的临床观察

李桂,柴友龙   

  1. 天津市南开医院第四外科
  • 收稿日期:2013-07-12 修回日期:2013-08-03 出版日期:2013-10-15 发布日期:2013-10-15
  • 通讯作者: 李桂

Observation of colorectal advanced carcinoma s treated by combination of Zilongjin pieces and chemotherapy

chai you long2   

  • Received:2013-07-12 Revised:2013-08-03 Published:2013-10-15 Online:2013-10-15

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摘要： 摘要：目的：观察紫龙金片联合由奥沙利铂(Oxaliplatin)、亚叶酸钙(CF)、氟尿嘧啶(5-Fu)组成的FOLFOX4方案及单用FOLFOX4方案化疗治疗大肠癌的疗效及不良反应。方法：45例接受化疗的大肠癌患者分为单用化疗组(对照组)及化疗并用紫龙金片组(治疗组)。结果：治疗组与对照组疗效评价比较，无统计学意义(p>0．05)；KPS评分治疗组与对照组比较，差异有统计学意义(p<0．05)；在骨髓抑制及恶心、呕吐副反应方面治疗组与对照组比较有统计学意义（P<0．05）。结论：紫龙金片联用FOLFOX4方案与单用FOLFOX4方案化疗治疗大肠癌相比能减轻化疗毒副作用，提高生活质量。

关键词: 结直肠肿瘤, 药物疗法, 联合, 生活质量, 紫龙金片

Abstract: 【Abstract】Objective：To observe the clinical effect of Zilongjin piece combined with chemotherapy in treatment of advanced colorectal carcinoma．Methods： Total of 45 patients were randomly divided into chemotherapy combined Zilongjin piece therapy group(treatment group，TG)and simple chemotherapy group(control group，CG)．Results： TG and CG were compared in zhe efficacy ，there was no significant difference between the 2 group(P>0．05)；KPS score of TG and CG were statistically significant difference (p