• 综述与讲座 •    

子宫内膜异位症的干细胞学说及其研究进展

王宇全,尹利荣   

  1. 天津医科大学第二医院妇科
  • 收稿日期:2013-01-21 修回日期:2013-05-02 出版日期:2013-10-15 发布日期:2013-10-15
  • 通讯作者: 王宇全

The progression of stem cell theory in endometriosis

WANG Yuquan ,YIN Li rong   

  1. Department of Gynecology, The Second Hospital of Tianjin Medical University
  • Received:2013-01-21 Revised:2013-05-02 Published:2013-10-15 Online:2013-10-15
  • Contact: WANG Yuquan

摘要:

 

关键词: 子宫内膜异位症, 干细胞, 发病机制

Abstract: Endometriosis is a common gynaecological disorder, and although extensively studied its etiopathogenic mechanisms remain unclear. Stem cells are undifferentiated cells that have the ability to self-renew as well as to produce more differentiated daughter cells in particular conditions. Recently, the identification of putative endometrial stem/progenitor cells (SPCs) has emerged as a possible origin of endometriotic lesions and a new mechanism for endometriosis etiology. This new hypothesis could account for the etilogy of all kinds of endometriosis, it has been raising considerable scientific and clinical interest not only for the breakthrough of the pathogenesis, but also for the new target on therapy.