• 短篇论著 •    下一篇

心房颤动伴肾功能不全的危险因素研究

李时双,谈维洁,孙津津,李安娜,王建昌   

  1. 北京空军总医院
  • 收稿日期:2013-02-27 修回日期:2013-07-03 出版日期:2013-11-15 发布日期:2013-11-15
  • 通讯作者: 王建昌

Risk factors of atrial fibrillation in patients with renal insufficiency

  • Received:2013-02-27 Revised:2013-07-03 Published:2013-11-15 Online:2013-11-15

摘要:

【摘要】  目的   分析心房颤动(AF)伴肾功能不全的危险因素。  方法   确诊为AF的住院患者529例,按AF是否合并肾功能不全分为2组,合并组303例,非合并组226例,比较2组相关临床资料,研究AF患者伴肾功能不全的可能危险因素。  结果  合并组的年龄、合并高血压、心功能不全及冠心病病史的比例高于非合并组(P<0.05),而2组性别、吸烟史、糖尿病、风湿性瓣膜病、甲亢、心肌病、特发性AF、左房扩大出现肾功能不全的发生率间差异无统计学意义。回归分析结果显示,年龄≥60岁、既往有高血压、冠心病及心功能不全是AF患者并发肾功能不全的危险因素。  结论  对老年性AF患者,加强其血压的管控、冠心病的防治及心功能的改善,对预防肾功能不全尤为重要

关键词: 心房颤动, 肾功能衰竭, 危险因素, Logistic模型, 回归分析

Abstract: Objective Analysis of hospitalized patients with atrial fibrillation (AF), renal dysfunction in patients with risk factors analysis. Methods Regression analysis of the clinical data of hospitalized patients(from January 2008 to December 2012 529 cases of patients) in the hospital diagnosis of atrial fibrillation , Atrial fibrillation whether renal insufficiency were divided into two groups, the clinical data were retrospectively analyzed to study possible risk factors for AF in patients with renal insufficiency. Results: Age, hypertension, heart failure and coronary heart disease history, the difference was statistically significant (P <0.05), while gender, smoking history, diabetes, rheumatic valvular disease, hyperthyroidism, cardiomyopathy, idiopathic AF, left atrial enlargement renal dysfunction incidence showed no significant difference (P> 0.05). Regression analysis: ≥ 60 years of age (P = 0.014, B = 0.036), hypertension (P = 0.024, B = 0.498), coronary heart disease (P = 0.034, B = 0.466), cardiac dysfunction (P = 0.000, B = 0.824). Conclusion: Age ≥ 60 years of age in patients with atrial fibrillation and renal dysfunction, hypertension, coronary heart disease and heart failure as the main factors, which elderly atrial fibrillation patients with renal insufficiency, pay attention to the control of their blood pressure and improved cardiac function,its secondary prevention of coronary heart disease in patients with coronary heart disease, is particularly important.