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物理疗法对糖尿病肾病患者微炎症状态影响的研究

奚悦   

  1. 辽宁医学院附属第三医院
  • 收稿日期:2012-08-28 修回日期:2012-12-17 出版日期:2013-04-15 发布日期:2013-04-15
  • 通讯作者: 奚悦

The Observation of Clinical Curative Effects of Physical Therapy and the Study of Impact on the State of Inflammation in the Diabetic Nephropathy Patient

  • Received:2012-08-28 Revised:2012-12-17 Published:2013-04-15 Online:2013-04-15

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摘要：

【摘要】目的 评价观察物理疗法对糖尿病肾病患者的治疗效果并初步探讨其机制。方法 选取糖尿病肾病Ⅲ期患者80例，随机分为物理疗法治疗组及黄葵药物对照组，观察2组治疗前及治疗15d后尿微量白蛋白排泄率（UAER）及急性时相血清淀粉样蛋白A（ASAA）、白细胞介素6（IL-6）、肿瘤坏死因子α（TNF-α）等指标水平的变化。结果治疗后2组患者UAER、ASAA、IL-6、TNF-α的水平较治疗前均明显下降（P<0.01）。治疗后，物理疗法治疗组的TNF-α（11.48±2.21）ng/L低于药物对照组（13.85±2.76）ng/L。结论 物理疗法治疗糖尿病肾病疗效确切，其对肾脏改善可能是通过降低糖尿病肾病患者的微炎症状态所致。

关键词: 糖尿病肾病, 物理治疗技术, 黄葵属, 血清淀粉样蛋白A, 白细胞介素6, 肿瘤坏死因子α, 尿微量白蛋

Abstract: Abstract Objective: To the observation of clinical curative effects of physical therapy in the diabetic nephropathy patients and the preliminary discussion the effective mechanism. Methods: The Ⅲ period of diabetic nephropathy patients have 80 cases, and randomly divided into treated group and control group，observed the change of index level about UAER、ASAA、IL-6、TNF-α after treatment 15 days. Results: After treatment, UAER of the diabetic nephropathy patients is significantly lower than before treatment (P < 0.05); the level of ASAA、IL-6、TNF-αare also obviously lower than before treatment (P < 0.05). Conclusion: The physical therapy is effective to cure the diabetic nephropathy Patients, and the improvement of the kidney, may be caused by reducing the inflammation state.