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18F-FDG PET/CT显像对结直肠癌术后患者治疗方案的影响

张悦1,高硕2,李亚军2,蔡莉2   

  1. 1. 天津医科大学第二医院
    2. 天津医科大学总医院
  • 收稿日期:2010-01-28 修回日期:2010-07-28 出版日期:2011-01-15 发布日期:2011-01-15
  • 通讯作者: 张悦

18F-FDG PET/CT affects restage and management of patients with colorectal cancer post-operation

  • Received:2010-01-28 Revised:2010-07-28 Published:2011-01-15 Online:2011-01-15
  • Contact: ZHANG Xiao Yue

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摘要： 目的：探讨18F-FDG PET/CT显像对结直肠癌术患者治疗方案的影响。方法：36例结直肠癌术后患者行全身18F-FDG PET/CT检查。以手术病理或临床常规影像检查随访结果作为最终诊断标准，分析比较PET/CT检查前、后患者再分期及治疗方案的更改情况。结果：PET/CT正确诊断34例，并正确更改其中17例患者的再分期及治疗方案：2例患者治疗方案内部发生更改，15例患者治疗方案在手术切除、放化疗及单纯随访三者之间发生更改，正确更改率为47.2%（17/36）。结论：18F-FDG PET/CT检查对结直肠癌术后患者的再分期及治疗方案产生积极正确影响。

关键词: 结直肠肿瘤, 癌, 肿瘤治疗方案, 氟脱氧葡萄糖F18, 正电子发射断层显像术, 体层摄影术, PET/CT

Abstract: Objective: To evaluate the impact of 18F-FDG PET/CT in restage and management of patients with colorectal cancer post-operation. Methods: 36 patients underwent whole-body 18F-FDG PET/CT. The diagnosis standards consisted of histopathology or follow-up by conventional imaging methods. Analyzing and comparing the restage and management before and after PET/CT. Results: PET/CT yielded a correct diagnosis in 34 out of 36 patients, and altered therapy management in 17 patients: 2 patients had therapy alteration within the management, 15 patients had therapy alteration among the surgery resection, the medical treatment (chemotherapy and radiotherapy) and follow-up. The change rate was 47.2 %( 17/36) Conclusion: 18F-FDG PET/CT improves restage and management of patients with colorectal cancer post-operation.

Key words: Colorectal Neoplasms, Carcinoma, Antineoplastic Protocols, Fluorodeoxyglucose F18, Positron-Emission Tomography, Tomography, PET/CT