天津医药

• 短篇论著 • 上一篇    下一篇

门冬氨酸钾镁在体外循环心内直视术中应用效果的临床观察

辛连峰1,赵聚钊1,薛玉良2   

  1. 1. 泰达国际心血管病医院麻醉科
    2. 天津泰达心血管病医院
  • 收稿日期:2010-03-11 修回日期:2010-08-17 出版日期:2011-01-15 发布日期:2011-01-15
  • 通讯作者: 辛连峰

  • Received:2010-03-11 Revised:2010-08-17 Published:2011-01-15 Online:2011-01-15

PDF (PC)

2237

摘要： 摘要 目的： 观察门冬氨酸钾镁在体外循环心内直视术患者手术过程中的应用效果。方法： 采用随机单盲原则将50例需行心脏手术的患者分为A组（试验组，25人）和B组（对照组，25人），两组在麻醉诱导后即刻（T2）、体外循环前即刻（T3）、体外循环后即刻（T4）和关胸后即刻（T5）则根据血气分析结果分别应用门冬氨酸钾镁（A组），和氯化钾（B组）进行补钾，并在术后计算两组补充钾离子总量，同时观察相应时间点患者血钾、血镁值以及对自动复跳率及术后转复窦律率观察。结果： 两组补钾效果无明显差异（P＞0.05），A组补镁疗效显著（P＜0.05），其他指标均无统计学差异。结论： 心脏手术过程中应用门冬氨酸钾镁可有效补充镁离子，对患者有益。

关键词: 钾镁天冬氨酸, 心脏, 体外循环, 心脏外科手术

Abstract: Abstract Objective: To evaluate the effect of potassium magnesium aspartate applied in cardiovascular surgeries. Methods: 50 patients undergoing cardiovascular surgeries were randomly divided in to two groups with 25 cases each. During the CPB, Kcl was conventionally given in both groups. However, during the other processes of the surgeries, potassium magnesium aspartate (group A) or Kcl (group B) was given to the patients to supply potassium according to the analysis of blood gas. The amount of potassium ion was calculated after the surgeries, and the value of blood potassium, magnism, the incidence of arrhythmia are observed in different time points. Results: There is no statistical difference in the potassium supplement and the incidence of arrhythmia in both groups（P＞0.05). The effect of magnesium supplement in Group A is more obvious than Group B（P＜0.05）。

Key words: Potassium Magnesium Aspartate, Heart, Extracorporeal Circulation, Cardiac Surgical Procedures