天津医药

天津医药 ›› 2016, Vol. 44 ›› Issue (6): 763-765.doi: 10.11958/20150230

• 临床研究 • 上一篇    下一篇

过度换气综合征患者手足搐搦危险因素分析

游道锋 1,乔秋阁 2,谢冰 1,姜相明 1,陈莹 1   

  1. 1河北医科大学第一医院急诊科 （邮编 050031）； 2河北医科大学第二医院东院普外科
  • 收稿日期:2015-10-15 修回日期:2015-12-17 出版日期:2016-06-15 发布日期:2016-07-04
  • 基金资助:
    河北省卫计委重点科技研究计划 （ZD20140508）

To analyze the risk factors of tetany in patients with hyperventilation syndrome

YOU Daofeng1, QIAO Qiuge2, XIE Bing1, JIANG Xiangming1, CHEN Ying1   

  1. 1 Department of Emergency, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China; 2 Department of General Surgery, the Second Hospital of Hebei Medical University
  • Received:2015-10-15 Revised:2015-12-17 Published:2016-06-15 Online:2016-07-04

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摘要： 摘要： 目的 探讨引起过度换气综合征患者出现手足搐搦的危险因素。方法 分析就诊于我院的过度换气综合征患者 103 例， 根据其是否出现手足搐搦， 分为手足搐搦组和非手足搐搦组。分析 2 组之间性别、 年龄、 电解质、 pH 值和二氧化碳分压[p(CO2)]的差异； 将 P < 0.1 的因素纳入二分类 Logistic 回归， 并采用 Logistic 回归 （Forward Wald 法） 分析患者出现手足搐搦的危险因素。结果 103 例患者中出现手足搐搦者 70 例 （68%）， 未出现 33 例 （32%）， 手足搐搦组血清 K+、 血清磷和 p(CO2) 均明显低于非手足搐搦组（P < 0.01）， 而手足搐搦组 pH 值高于非手足搐搦组（P < 0.01）。2 组性别、 年龄、 血清 Na+、 血清 Cl-、 血清钙 （结合钙和离子 Ca2+）、 离子 Ca2+和血清 Mg2+水平差异无统计学意义 （P > 0.05）。二分类 Logistic 回归分析显示年龄小、 血清 K+降低、 血清磷降低和 p(CO2) 降低是手足搐搦的危险因素。结论 年龄小、 血清 K+水平降低、 血清磷降低和 p(CO2)降低是过度换气综合征患者出现手足搐搦的危险因素。

关键词: 通气过度, 手足搐搦, 低钙血症, 低磷血症, 低钾血症, 血气分析, 危险因素

Abstract: Abstract： Objective To explore the risk factors causing tetany in patients with hyperventilation syndrome. Meth⁃ ods A total of 103 patients with hyperventilation syndrome treated in our hospital were included in this study. According to whether there was tetany, patients were divided into tetany group and non-tetany group. Values of gender, age, electrolyte, pH and p(CO2) were analysed between two groups. The factors of P < 0.1 were engaged in binary Logistic regression. Logistic regression (Forward Wald) was used to analyze the risk factors of tetany in patients with hyperventilation syndrome. Re⁃ sults In 103 patients there were 70 patients with tetany (68%), 33 patients without tetany(32%). The serum K+, serum phos⁃ phorus and p(CO2) values were significantly lower in tetany group than those of non-tetany group (P < 0.01), while the pH value was significantly higher in tetany group than those of non-tetany group (P < 0.01). There were no significant differences in gen⁃ der, age, serum Na+, serum Cl-, serum calcium (bound calcium and ionized calcium), ionized calcium and serum Mg2+ levels be⁃ tween two groups (P > 0.05). It was revealed that the younger age, the lower level of the serum K+, serum phosphorus and p(CO2) were the risk factors of tetany through binary Logistic regression analysis. Conclusion The risk factors of tetany in patients with hyperventilation syndrome include younger age, lower level of serum K+ and serum phosphorus and reduced p(CO2).

Key words: hyperventilation, tetany, hypocalcemia, hypophosphatemia, hypokalemia, blood gas analysis, risk factors