Abstract: Abstract: Objective To explore the psychosocial factors in patients with pelvic organ prolapse and depression.
Methods A total of 199 patients with pelvic organ prolapse screened from a certain population in Xinjiang were randomly
selected in this study. The depressive symptoms were assessed by Hamilton depression scale (HAMD-24). For 199 patients,
62 cases were accompanied by depressive symptoms (depression group), and 137 without depression symptom (nondepression group). Hamilton anxiety scale (HAMA-14), Eysenck personality questionnaire (EPQ), Simplified coping style
questionnaire (SCSQ) and Social support rating scale (SSRS) were used to evaluate two groups of patients. Results
Depression was found in 31.2% of patients with pelvic organ prolapse. There were statistically significant differences in
anxiety, neuroticism, negative coping and subjective support scores between the depression group and the non-depression
group (P＜0.05). It was found that anxiety and neuroticism were risk factors for patients of pelvic organ prolapse combined
with depression (OR=1.691 and 1.819). Conclusion Medical staff should pay attention to the psychological intervention of
the related factors of patients with pelvic organ prolapse and depression, improve the mental health of patients, and promote
conservative treatment and surgical treatment of pelvic organ prolapse.

Key words: pelvic organ prolapse, depressive disorder, anxiety disorders, personality, social support, coping skills