Abstract: Abstract：Neutrophil extracellular traps (NETs) are a newly recognized structure in recent years, which is involved in the pathogenesis of autoimmune diseases, thrombosis and inflammatory reaction. NETs can be induced to different forms of reticular structure by a variety of trigger factors and can be quantified by various techniques. According to the different subjects, the analysis methods include morphological observation, detection of cell free DNA and neutrophil elastasemyeloperoxidase, citrullinated histone and other protein components. In this paper, the advantages and disadvantages of these detection techniques are summarized, which will provide useful reference for the further development of the application of NETs in the early diagnosis and prognosis judgment of related diseases.

Key words: neutrophil extracellular traps, morphological and microscopic findings, cell-free DNA, neutrophil elastase, myeloperoxidase