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Notch Signaling in Renal Interstitial Fibrosis and Retinoic Acid

DU Xuan 1,TU Weiping 2   

  1. 1. Department of Nephrology, the Second Affiliated Hospital oNanchang 330006, Chinaf Medical College of Nanchang University,
    2. Department of Nephrology, the Second Affiliated Hospital of Medical College of Nanchang University,Nanchang 330006, China
  • Received:2013-11-15 Revised:2014-05-28 Published:2014-09-15 Online:2014-09-15
  • Contact: DU Xuan

Abstract: Abstract:The effect on Renal Interstitial Fibrosis(RIF) by Retinoic Acid(RA) is wide and important. Notch signaling is known to play an important role in the pathology route of RIF. This paper summarizes recent research progress on the effect on RIF and Notch signaling by RA. Interruption of Notch signaling by RA might be a potential anti-fibrotic strategy in RIF.

Key words: retinoic acid, Notch signaling, renal interstitial fibrosis