Abstract: Objective To investigate the efficacy of colon dialysis therapy with integrated traditional Chinese and Western medicine and artificial liver support system with hepatic encephalopathy. Methods 74 cases of hepatic encephalopathy were divided into two groups: treated group(38 cases) and control group(36 cases) and treated with comprehensive management and artificial liver treatment. The patients in treatment group were treated with colon dialysis therapy on the base of routine treatment. The changes of symptom, prognosis, liver function, PTA, blood ammonia were observed before and after the treatment. ? Results The survival rate in treated group(84.21%) was higher than that in control group(58.33%)(χ2＝6.091，P＜0.05). The recovery period of unconsciousness of patients in treated group (32.88±8.34)h was much shorter than those in control group (45.12±9.68)h (P<0.01). The totle effective rate for hepatic encephalopathy treatment in treated group (78.95%) was much higher than those in control group (52.78%)(χ2＝5.659，P＜0.05). Significant difference of Bil, PTA, and blood ammonia were shown in the treated group(P<0.01) before and after treatment, and between groups after treatment (P<0.01). Conclusion The colon dialysis is effective in hepatic encephalopathy treatment, which can shorten the unconsciousness time, increase the survival rate, decrease the levels of bilirubin and blood, ammonia and shorten prothrombin time.

Key words: colon dialysis therapy with integrated traditional Chinese and Western medicine, liver failure, hepatic encephalopathy, artificial liver support system