Abstract: Summary Background:With a large area of soft tissue trauma were difficult to repair,it not only need a long time for treatment,but also so expensive.As a result,their economic burden was increased for those patients who lived in less-developed area.Nowadays,vacuum sealing drainage technique for the repair of various wounds have been to applicate widely. Purpose:Discuss on vacuum sealing drainage treatment of a large area of soft tissue trauma and efficacy in less-developed area.Method:The 74 patients were divided into VSD group 40 cases and control group with 34 cases.Those in control group were given routine dressing change after debridement .Those in VSD group were covered with VSD dressing and continued negative pressure suction after debridement.We removed the VSD dressing 5~10 days later.Then evaluated and appraised the curative effect according to the comparison of two groups of the wound cleaning time、two stage operation time、the wound area after treatment 、frequency of dressing changes、skin effect、application of antibiotic cost、the total duration of hospitalization and so on.Result:As a result,the indicators in VSD group were better than the control group.The differences between the two group were statistically significant.(p＜0.05~0.01）In conclusion,the VSD treatment of a large area of soft tissue trauma is more effective than the traditional method.The VSD treatment will develop well in less-developed area because it reduces medical costs significantly.

Key words: vacuum sealing drainage, limbs, soft tissue, trauma.