Abstract: Objective: To investigate the relationship between the vascular impairment not dementia and the risk factors, this will facilitate the diagnosis and therapy as earlier as possible. Methods: Collect the patients who have the risk factor of ischemic cerebrovascular disease from the ward or the clinic in Tianjin general hospital from April 2009 till August 2009.The patients were divided to 2 groups. The 2 groups are VCIND group and the control group. All the patients have been detected the blood pressure and completed some related chemical and image examinations. Then compare the clinical data between the 2 groups. Result: There are variations in statistics between these two groups in the comparison of rations of diabetes mellitus, hypercholesteremia, hypertriglyceridemia, hyperhomocytinemia, major artery stenosis and white matter lesion. There is also variation in statistics of the score of MoCA between single risk factor group and the control group respectively. We divided all the patient into high risk group and low risk factor group by the score of ESSEN, we can find the variation in statistics by the comparison of MoCA between this 2 group. Conclusion: There are apparent correlation between these risk factors (except hypertension) and VCIND. Any single factor can lead to VCIND. The cognition will be damaged much more severely if the risk factors is more.

Key words: Vascular Cognitive Impairment Not Dementia, Vascular Dementia, Vascular Cognitive Impairment