Abstract: [Abstract] Prostate cancer is the most prevalent malignancies in elderly men. At present, gene therapy is the most po?
tential treatment for late- stage prostate cancer. However, virus vector or nonvirus vector are less safety, weaker targeting function and higher immunogenic. Ultrasound microcapsular contrast agent as a drug transporter is a new type of disease targeted treatment strategies. It has provided a high-targeted, an effective and a safety gene therapy for prostate cancer, and brings a new hope for late-stage prostate cancer patients. This article aims to summarize the recent progress in using the microbubble technology in prostate cancer.