Abstract: Abstract Object To investigate the feasibility of bi-level positive airway pressure (BiPAP) mechanical ventilation applied in curing acute left cardiac dysfunction (ALCD). Methods Forty-two patients with ALCD were divided randomly into 2 groups: noninvasive positive pressure mechanical ventilation group in which the patients got the treatment of BiPAP mechanical ventilation, and invasive mechanical ventilation group. Both two groups all accepted the same routine drug therapy. Heart beats, arterial pressure, arterial blood gas analysis, and clinical symptoms before and after the treatment were compared between the two groups. Results Satisfied effects were obtained in both groups, and there was no significant difference between the two groups in heart beats, arterial pressure, arterial blood gas analysis, and clinical symptoms before and after treatment (P>0.05). Conclusions Patients with ALCD can obtain the benefit of early application of IPPV in improving clinical symptoms, redressing hypoxemia, and prompting heart function.

Key words: Acute left cardiac dysfunction, Bi-level positive airway pressure, Mechanical ventilation