天津医药 ›› 2019, Vol. 47 ›› Issue (9): 937-942.doi: 10.11958/20192202

• 临床研究 • 上一篇    下一篇

自锚式侧路腰椎椎体间融合术的设计与应用

徐宝山,刘阳,姜洪丰,刘越,王涛,黎宁,许海委,黄洪超,吉宁   

  1. 基金项目:国家自然科学基金资助项目(31670983) 作者单位:天津医院微创脊柱外科(邮编300211) 作者简介:徐宝山(1971),男,主任医师,教授,博士生导师,主要从事微创脊柱外科、椎间盘生物学修复研究
  • 收稿日期:2019-07-19 修回日期:2019-07-23 出版日期:2019-09-15 发布日期:2019-09-18
  • 通讯作者: 徐宝山 E-mail:xubaoshan99@126.com
  • 基金资助:
    国家自然科学基金资助项目

The design and application of self-anchored lateral lumbar interbody fusion

XU Bao-shan, LIU Yang, JIANG Hong-feng, LIU Yue, WANG Tao, LI Ning, XU Hai-wei, HUANG Hong-chao, JI Ning   

  1. Department of Minimally Invasive Spine Surgery, Tianjin Hospital, Tianjin 300211, China
  • Received:2019-07-19 Revised:2019-07-23 Published:2019-09-15 Online:2019-09-18
  • Contact: XU Baoshan E-mail:xubaoshan99@126.com
  • Supported by:
    projects funded by the National Natural Science Foundation of China

摘要: 目的 评估自锚式侧路腰椎椎间融合术(SA-LLIF)的价值和疗效,避免后路内固定,简化手术步骤。方 法 选择2019年3月—6月在我科手术治疗的腰椎退变性疾病患者11例,男3例,女8例,年龄55~76岁,均有腰腿 痛,站立和活动时加重,卧床时症状减轻一半以上或消失,包括腰椎失稳7例,滑脱4例(Ⅰ度3例,Ⅱ度1例),其中2 例伴有骨质疏松症,2例伴有脊柱侧凸,责任节段L2~3 1例、L3~4 4例、L4~5 4例、L2~4 1例、L3~5 1例。应用带锚定嵌片的零 切迹融合器经斜侧入路行腰椎椎体间融合术,避免后路内固定。全麻后患者呈右侧卧位,经左侧小切口腹膜外入路 显露腰大肌前缘,向后适度牵开腰大肌显露责任椎间隙左侧方,处理椎间隙后植入合适大小的填满异体骨的融合 器,将远近侧两个锚定嵌片依次插入融合器和邻近椎体,锁定融合器和椎体,均未放置引流。记录患者术前、术中、 术后有关参数,并进行随访。采用疼痛视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI)评价临床疗效,X线片评 估腰椎前凸角(LL)、椎间隙高度(DH)、滑脱率(S)、cage移位和下沉情况。结果 11例患者均顺利完成手术,手术时 间65~110 min,平均(78.0±21.5)min,术中出血15~60 mL,平均(35.0±23.2)mL,均未发生神经、血管损伤等并发症。 术后次日带腰围下地活动。VAS评分自术前(6.2±0.8)分降至(1.7±0.5)分,ODI评分自术前47.8%±14.9%降至术后 11.2%±3.2%,差异均有统计学意义。术后X线片示脊柱序列恢复满意,内植物位置良好,LL自术前36.4°±10.2°恢复 至术后48.0°±10.7°,DH自术前(8.3±2.5)mm恢复至(13.3±3.3)mm,S自术前26.7%±4.4%恢复至术后10.3%±5.3%,差 异均有统计学意义。随访期间所有患者均未出现cage移位,1例肥胖患者融合器下沉约2 mm,其他患者均未出现融 合器明显下沉。结论 SA-LLIF可以提供良好的即刻稳定性,避免后路内固定,操作简单,疗效优良。

关键词: 腰椎, 椎间盘退行性变, 脊柱融合术, 外科手术, 微创性, 侧方入路

Abstract: Objective To evaluate the value and efficacy of self-anchored lateral lumbar interbody fusion (SA-LLIF), avoid posterior internal fixation and simplify the surgical procedure. Methods Eleven patients with lumbar degenerative disease treated in our hospital from March to June 2019 were enrolled in this study, including 3 males and 8 females (aged 55-76 years). All patients had low back pain and leg pain, which aggravated when standing and moving and alleviated or disappeared when staying in bed. The imaging results revealed that there were 7 cases of lumbar instability, 4 cases of spondylolisthesis (grade Ⅰin 3 cases, grade Ⅱ in 1 case), 2 of them with scoliosis and 2 with osteoporosis. The fusion level included L 2-3 in 1 case, L3-4 in 4 cases, L4-5 in 4 cases, L2-4 in 1 case and L3-5 in 1 case. Zero-profile self-anchored cage was used for lateral lumbar interbody fusion to avoid posterior internal fixation. After general anesthesia, the patient was in right decubitus position. The anterior edge of psoas major muscle was exposed through left small incision and extraperitoneal approach, the left side of the responsible intervertebral space was exposed by properly retracted psoas major muscle. After the intervertebral space was prepared, a suitable size of fusion cage filled with allograft was implanted. Two anchoring plates were inserted into the cage and the caudal and cephalic vertebral body, and the fusion cage was locked. The clinical efficacy was evaluated by visual analogue scale (VAS) and Oswestry dysfunction index (ODI). The lumbar lordosis (LL), disc height (DH), slippage rate (S) and sinking were evaluated by X-ray. Results The operation was performed successfully in all the 11 patients. The operation time was 65-110 minutes, with an average of (78.0±21.5) minutes. The intraoperative blood loss was 15-60 mL, with an average of (35.0 ± 23.2) mL. No severe complication such as nerve or blood vessel injury was occurred. The patients were encouraged to ambulated next day after operation with soft brace. The VAS score was significantly decreased from preoperative (6.2±0.8) to (1.70±0.5) after surgery, and ODI score was significantly decreased from (47.8%±14.9%) to (11.2%±3.2%). Postoperative X-ray showed that the spine alignment recovered satisfactorily, the LL recovered from (36.4°±10.2°) to (48.0°±10.7°), DH recovered from (8.3±2.5) mm to (13.3±3.3) mm, and the S recovered from (26.7%±4.4%) to (10.3%±5.3%). No cage displacement was found during follow-up, and sinking of cage was found in only one obesity woman. Conclusion SA-LLIF can provide immediate stability with good results, avoid posterior internal fixation.

Key words: lumbar vertebrae, intervertebral disc degeneration, spinal fusion, surgical procedure, minimally invasive, lateral approach