天津医药

• 流行病学调查 • 上一篇    下一篇

涿州市尿路结石的流行病学现状及危险因素分析

王艳玲1,王轩久2   

  1. 1. 河北省涿州市医院
    2. 涿州市医院泌尿外科
  • 收稿日期:2013-10-24 修回日期:2013-12-02 出版日期:2014-01-15 发布日期:2014-01-15
  • 通讯作者: 王轩久

Study on epideniology ang risk factors of Urinary calculus in Zhuozhou city

  • Received:2013-10-24 Revised:2013-12-02 Published:2014-01-15 Online:2014-01-15

PDF (PC)

2985

摘要：

目的 分析涿州市尿路结石的流行病学现状及危险因素。方法 采用分层整群随机抽样法对19 446例涿州市居民进行调查问卷， 内容包括体质量指数 （BMI）、 日饮水量、 甜食、 膳食口味、 食用油、 高蛋白膳食、 家族史等7种因素。采用1 ∶1比例选取与结石组基线资料匹配的正常人群为对照组， 比较2组上述7种因素。采用Logistic回归从BMI、 饮食习惯、 结石家族史等多方面综合分析尿路结石发病的危险因素。结果 17 854份有效问卷中， 明确诊断为尿路结石的患者为1 752例 （9.8%）， 男1 125例， 女627例， 30~岁和40~岁组最多， 共843例 （48.04%）。发病集中在第2、 3季度， 以输尿管结石为主。结石组与对照组间BMI、 日饮水量、 甜食、 膳食口味、 食用油、 高蛋白膳食、 尿路结石病家族史比较差异均有统计学意义。Logistic回归分析结果显示， 日平均饮水量较多、 BMI较低和喜食植物油是尿路结石的保护因素， 膳食口味偏咸、 喜欢甜食、 高蛋白饮食频率较高、 有家族史是尿路结石的危险因素。结论 尿路结石防治重点措施是控制体质量， 多饮水， 控制高蛋白、 高糖、 高盐食物的摄入。

关键词: 尿路结石, 流行病学, 危险因素, 分析

Abstract: [Abstract] Objective To analyze the pathogenetic charateristics and risk factors of urinary calculus in Zhuozhou city. Methods 17854 residents with the age above 15 were surveyed from 2010 to 2013, the questionnaire include sex, age, dietary habits, etc. The methods for measurement included questionnaire, face-to-face interview,clinical examination and abdominal ultrasonography. The data processing, dataset and analyses were performed using Foxpro 6.0 and Spss 17.0. Condition logistic regession was performed to investigate the association between body mass index (BMI), drinking water, eating salt food, eating sweat food, high protein food, oil, past history of urinary calculus, family history of urinary calculus and urinary calculus. Results There were 1752 urinary calculus patients among 17854 follow-up members, the incidence was 9.81%. Twenties to fifties were the high illness age stage, accounted for 48.63%. Summer and Autumn were the high incidence seasons and the most cases of urinary calculus in the city were ureternal stones, accounted for 82.02%.Condition logistic regression analysis showed BMI, drinking water, eating salt food, eating sweat food, high protein food, oil, past history of urinary calculus, family history of urinary calculus with a elebated risk of urinary calculus.（HR=2.761,95% CI=1.546～4.929；HR=1.914,95% CI=1.272～2.881；HR=3.383,95% CI=2.133～5.362；HR=4.509,95% CI=2.457～8.277；HR=2.753,95% CI=1.710～4.432；HR=2.222,95% CI=1.012～4.880；HR=2.763,95% CI=1.534～4.948；HR=2.756,95% CI=1.682～4.453）. Conclusion The illness characteristic of urinary calculus in our city is similar to that the big clan cases prerelence disease investigation in the country , controling body mass and changing the inappropriate habitual eating patterns and generalizing the use of proportioning dietary should be the main measures to prevent urinary calculus.

Key words: Urinary calculus, Epidemiology, Risk factor, Analysis