天津医药

天津医药 ›› 2017, Vol. 45 ›› Issue (9): 931-934.doi: 10.11958/20170486

• 临床研究 • 上一篇    下一篇

额叶癫痫患者睡眠障碍的特征研究

侯玉莹,宋毅军   

  1. 天津医科大学总医院神经内科
  • 收稿日期:2017-04-18 修回日期:2017-08-13 出版日期:2017-09-15 发布日期:2017-09-25
  • 通讯作者: 宋毅军 E-mail:songyijun2000@126.com
  • 基金资助:
    天津市应用基础与前沿技术研究计划

The study of the sleep disorders characteristics in frontal lobe epilepsy

HOU Yu-ying, SONG Yi-jun△   

  • Received:2017-04-18 Revised:2017-08-13 Published:2017-09-15 Online:2017-09-25
  • Contact: yijun song E-mail:songyijun2000@126.com

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摘要： 摘要：目的 通过多导睡眠监测及主观量表以研究额叶癫痫患者睡眠事件特征，并讨睡眠障碍特征。方法 选取18名额叶癫痫患者与15名健康对照者组成实验组，对两组进行多导睡眠监测及临床量表评估，分析所得数据。结果 与正常对照组相比，额叶癫痫组总卧床时间[(503.22±62.33)分]、入睡后觉醒时间[（54.11±18.97）分]延长，总睡眠期转换次数[（161.17±56.83）次]、每小时睡眠期转换次数[（22.6±6.25）次]、N1[(42.56±15.26)次]、N2[(57.28±26.57)次]及清醒期[(48.76±10.62)次]转换次数增加；并且BDI-II[(9.33±5.01)分]及疲劳评分[(5.72±3.36)分]增加。结论 FLE患者存在睡眠障碍，FLE患者睡眠障碍与发作频率及抑郁程度相关。

关键词: 额叶癫痫, 睡眠障碍, 疲劳, 抑郁

Abstract: This study aimed to investigate the sleep disorders characteristic in frontal lobe epilepsy（frontal lobe epilepsy，FLE）through polysomnography and subjective questionnaires. Methods 18 FLE patients and 15 healthy subjects were recruited to our study. Every subject were evaluated by whole-night polysomnography and subjective questionnaires. Results Compared with controls, the FLE demonstrated an obviously increase in total time in bed[(503.22±62.33)min], wake after sleep onset[（54.11±18.97）min], number of sleep stage shifts in total sleep time[（161.17±56.83）], the number of sleep stage shifts per an hour[（22.6±6.25）], the number of NREM1 stage shifts[(42.56±15.26)] and NREM2 stage shifts[(57.28±26.57)], number of wake stage[(48.76±10.62)]. Meanwhile, FLE showed higher scores in BDI-II [(9.33±5.01)]and Fatigue scale-14[(5.72±3.36)分] compared with controls. Conclusion The sleep disorders and sleep disruption can be found in FLE, furthermore, the sleep disorders in FLE is related with depression and seizures frequency.

Key words: frontal lobe epilepsy, sleep disorders, fatigue, depression