天津医药

天津医药 ›› 2018, Vol. 46 ›› Issue (5): 544-547.doi: 10.11958/20180124

• 流行病学调查 • 上一篇    下一篇

2004—2016年郑州市细菌性痢疾流行特征及病原学分析

段晶晶， 安戈， 刘江华， 徐兰英， 李肖红， 韩同武   

  1. 郑州市疾病预防控制中心 （邮编450007）
  • 收稿日期:2018-01-22 修回日期:2018-03-15 出版日期:2018-05-15 发布日期:2018-05-15
  • 通讯作者: 段晶晶 E-mail:djj55@126.com
  • 基金资助:
    感染性腹泻病原菌PFGE同源性追踪调查研究

Epidemiological characteristics and pathogenic analysis of bacillary dysentery in Zhengzhou city from 2004 to 2016

DUAN Jing-jing, AN Ge, LIU Jiang-hua, XU Lan-ying, LI Xiao-hong, HAN Tong-wu   

  1. Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China
  • Received:2018-01-22 Revised:2018-03-15 Published:2018-05-15 Online:2018-05-15

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摘要： 摘要： 目的 了解郑州市细菌性痢疾的流行情况及病原学特征， 为制定防控措施和策略提供参考依据。方法 采用描述流行病学方法对2004—2016年郑州市细菌性痢疾监测数据及菌型检测结果进行分析。结果 2004—2016 年郑州市共报告细菌性痢疾29 284例， 年均发病率为31.28/10万， 总体呈下降趋势 （χ2 趋势=103.60， P＜0.001）。发病高峰为每年的5—10月， 市区高于郊县， 男性发病率高于女性， 3岁以下幼儿是主要的发病人群， 职业以散居儿童为主。 2004—2016年共分离鉴定志贺菌387株， 主要是福氏志贺菌 （280株， 72.35%）， 血清型以F2a为主； 同时宋内志贺菌检出率呈上升趋势。结论 细菌性痢疾仍然是郑州市需要防控的重点传染病， 应在流行季节加大对重点地区、 重点人群的宣教力度， 采取综合防控措施， 进一步降低其发病水平。

关键词: 痢疾, 杆菌性, 流行病学研究, 病原, 统计学分布, 血清型, 郑州

Abstract: Abstract：Objective To understand the epidemic and etiological characteristics of bacillary dysentery and provide scientific evidence for the prevention strategies. Methods The surveillance data and serotyping of bacillary dysentery in Zhengzhou city from 2004 to 2016 were analyzed by descriptive epidemiological method. Results A total of 29 284 cases of bacillary dysentery were reported in Zhengzhou from 2004-2016. The average annual incidence was 31.28 per 100 000 and decreased annually (χ2 =103.60, P＜0.001). The peak season was from May to October. The incidence was higher in city than that of county, and male was higher than female. The majority of the bacillary dysentery cases was children under 3 years old, and scattered children were the main population at risk. A total of 385 Shigella strains were isolated and identified from 2004 to 2016, and 72.35% (280 strains) of strains were Shigella flexneri. F2a subtype was dominated, but the detective rate of Shigella sonnei was increased gradually. Conclusion Bacillary dysentery is still one of important infectious diseases in Zhengzhou, comprehensive measures should be taken to decrease the incidence including health education in targeted area and people in epidemic season.

Key words: dysentery, bacillary, epidemiologic studies, noxae, statistical distributions, serotype, Zhengzhou