关键词: 结肠镜检查, 补液疗法, 碳水化合物, 老年人, 血压, 心率, 术后疲劳综合征

Abstract: Objective　To investigate the clinical application value of oral multi-dimensional carbohydrates 2 h before painless colonoscopy in elderly patients. Methods　A total of 120 elderly patients with painless colonoscopy were selected, and they were randomly divided into oral multi-dimensional carbohydrate group (energy mixture group), intravenous infusion of sodium potassium magnesium calcium and glucose injection group (infusion control group) and control group (blank control group). There were 40 cases in each group. The blank control group was prepared according to the traditional intestinal preparation, without any rehydration intervention. The energy mixture group was given 5 mL/kg of energy mixture 2 h before painless colonoscopy, and the maximum dosage was not more than 400 mL. The infusion control group was given 500 mL sodium potassium magnesium calcium glucose injection 2 h before painless colonoscopy. The colonoscopy operation time, propofol dosage, recovery time, postanesthesia care unit (PACU) stay time, vasoactive drug use, thirst, visual analogue scale (VAS) of hunger and fatigue, christensen postoperative fatigue score were recorded, and systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and heart rate (HR) were measured at the time points of entering the room (T0), induction (T1), entering the mirror (T2), withdrawing the mirror (T3) and entering the PACU (T4). After the examination, adverse reactions of the three groups were recorded. Results　There were no significant differences in colonoscopy operation time and propofol dosage between the three groups (P＞0.05). Compared with the blank control group,the recovery time and PACU stay time were significantly shorter in the energy mixture group and the infusion control group, and the utilization rate and repeated use rate of vasoactive drugs decreased (P＜0.05). At the time of T1, T2 and T4, HR values were significantly lower in energy mixture group and infusion control group than those in blank control group (P＜0.05). At the time of T2, values of SBP, DBP and MAP were higher in energy mixture group and infusion control group than those in blank control group (P＜0.05). At the time of leaving PACU, the scores of thirst and hunger were significantly lower in the energy mixture group than those in the infusion control group and the blank control group (P＜0.05). After the examination, compared with the blank control group, the incidence of severe hypotension and prolonged recovery time and the scores of fatigue out of room were significantly reduced in the energy mixture group and infusion control group (P＜0.05). Conclusion　Oral administration of multi-dimensional carbohydrates 2 h before colonoscopy in elderly patients can reduce the fluctuation of heart rate and blood pressure during the examination, shorten the recovery time, and reduce hunger and fatigue degree after operation.

Key words: colonoscopy, fluid therapy, carbohydrates, aged, blood pressure, heart rate, postoperative fatigue syndrome