天津医药

天津医药 ›› 2018, Vol. 46 ›› Issue (6): 651-653.doi: 10.11958/20180020

• 临床研究 • 上一篇    下一篇

肝硬化合并以上消化道大出血为首发症状的胃弥漫大B细胞淋巴瘤一例

徐佰国，刘磊，李隽，尹伟利，王菲，杨言开   

  1. 天津市第三中心医院，天津市肝胆疾病研究所，天津市人工细胞重点实验室，卫生部人工细胞工程技术研究中心（邮编300170）
  • 收稿日期:2018-01-03 修回日期:2018-03-22 出版日期:2018-06-15 发布日期:2018-07-05
  • 通讯作者: 杨言开 E-mail:yangyankai@126.com

The upper gastrointestinal hemorrhage as the initial symptom in gastric diffuse large B-cell lymphoma combined with liver cirrhosis: a case report

XU Bai-guo, LIU Lei, LI Jun, YIN Wei-li, WANG Fei, YANG Yan-kai   

  1. Department of Gastroenterology and Hepatology, Tianjin Third Central Hospital；Tianjin Institute of Hepatobiliary Disease,Tianjin Key Laboratory of Artificial Cell; Artificial Cell Engineering Technology Research Center ofPublic Health Ministry, Tianjin 300170, Chin
  • Received:2018-01-03 Revised:2018-03-22 Published:2018-06-15 Online:2018-07-05

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摘要： 弥漫大B细胞淋巴瘤（DLBCL）是非霍奇金淋巴瘤（NHL）中发病率最高的一类弥漫生长的B细胞淋巴瘤。该病以进行性淋巴结肿大为最主要的临床表现，可结外发病，临床表现多样性，易被误诊。本文报告为以上消化道出血为首发症状，合并肝硬化，内镜表现为胃溃疡的胃DLBCL患者1例。期望通过对本病例分析以提高对DLBCL的认识和诊治水平。

关键词: 胃肿瘤, 淋巴瘤, 大B细胞, 弥漫性, 消化性溃疡出血, 肝硬化

Abstract: Diffuse large B-cell lymphoma (DLBCL) is the most prevalent type of diffuse B-cell lymphoma in nonhodgkin lymphoma (NHL). The progressive enlarging lymphonodus is the most common clinical manifestation of this disease. DLBCL often appears heterogeneous presentations. It is easy to be misdiagnosed. Here, we reviewed a case of DLBCL with liver cirrhosis, in which the initial symptom was upper gastrointestinal hemorrhage, and the endoscopic examination showing gastric ulcer. We hope to improve the understanding and diagnosis and treatment levels of DLBCL by analyzing this case.

Key words: stomach neoplasms, lymphoma, large B-cell, diffuse, peptic ulcer hemorrhage, liver cirrhosis