红金消结胶囊治疗麦默通微创旋切术后血肿的临床观察

doi:10.11958/20241932

天津医药 ›› 2025, Vol. 53 ›› Issue (4): 389-392.doi: 10.11958/20241932

红金消结胶囊治疗麦默通微创旋切术后血肿的临床观察

孙云芸¹(), 闵美林¹^,^△(), 许丽波²

1 无锡市中医医院甲乳科（邮编214000）
2 超声科

收稿日期:2024-11-21 修回日期:2025-02-13 出版日期:2025-04-15 发布日期:2025-04-17
通讯作者: ^△ E-mail：ml570088@126.com
作者简介:孙云芸（1986），女，副主任中医师，主要从事乳腺疾病中医治疗方面研究。E-mail：syyzhuce@126.com
基金资助:
2023年无锡市中医药管理局项目(ZYYB08)

Clinical observation of HongjinXiaojie capsule in the treatment of hematomas after minimally invasive vacuum-assisted Mammotome mastectomy

SUN Yunyun¹(), MIN Meilin¹^,^△(), XU Libo²

1 Department of Thyroid and Breast
2 Department of Ultrasound, Wuxi Traditional Chinese Medicine Hospital, Wuxi 214000, China

Received:2024-11-21 Revised:2025-02-13 Published:2025-04-15 Online:2025-04-17
Contact: ^△ E-mail：ml570088@126.com

孙云芸, 闵美林, 许丽波. 红金消结胶囊治疗麦默通微创旋切术后血肿的临床观察[J]. 天津医药, 2025, 53(4): 389-392.

SUN Yunyun, MIN Meilin, XU Libo. Clinical observation of HongjinXiaojie capsule in the treatment of hematomas after minimally invasive vacuum-assisted Mammotome mastectomy[J]. Tianjin Medical Journal, 2025, 53(4): 389-392.

摘要/Abstract

摘要：

目的通过观察红金消结胶囊治疗麦默通微创旋切术后血肿的疗效，以期确定麦默通微创旋切术后常见的血肿和疼痛等临床并发症的治疗方法。方法选取在我院行乳房肿块麦默通微创旋切术，术后72 h形成血肿患者70例。按治疗方法不同，将患者分为观察组及对照组各35例，对照组予单纯热敷外治，观察组予局部热敷及口服红金消结胶囊治疗4周，术后每4周随访1次，连续随访12周，复查彩超观察血肿大小。比较2组随访期间疼痛视觉模拟量表（VAS）评分和气滞血瘀中医证候积分变化。结果术后4周，观察组疼痛VAS评分明显低于对照组[（2（1，3）分vs. 3（2，4）分，P<0.05）]，血肿比例低于对照组（45.7% vs. 82.9%，P<0.05）。术后12周，2组疼痛VAS评分及血肿比例差异无统计学意义。术后4周及12周观察组中医症候积分均低于对照组（P<0.05）。结论红金消结胶囊可促进麦默通术后血肿吸收，有效缓解乳房疼痛，安全性较高，具有临床推广价值。

关键词: 乳房, 血肿, 麦默通微创旋切术, 红金消结胶囊, 吸收与散瘀

Abstract:

Objective To observe the efficacy of Hongjin Xiaojie capsules in treating hematoma after Mammotome minimally invasive excision and to determine the common clinical complications such as hematoma and pain after the surgery. Methods A total of 70 patients who developed hematoma within 72 hours after Mammotome minimally invasive excision for breast lumps at our hospital were selected. Based on different treatment methods, patients were divided into the observation group and the control group, with 35 cases in each group. The control group received only external hot compress treatment, while the observation group received local hot compress combined with oral administration of Hongjin Xiaojie Capsule for 4 weeks. Follow-up was conducted every 4 weeks postoperatively for a total of 12 weeks. Color ultrasound was performed to monitor the size of the hematoma. Changes in pain visual analog scale (VAS) scores and traditional Chinese medicine (TCM) syndrome scores for blood stasis were compared between the two groups of patients during follow-up. Results Four weeks after operation, the pain VAS score was significantly lower in the observation group than that in the control group [2 (1, 3) points vs. 3 (2, 4) points, P<0.05], and the proportion of hematoma was lower in the observation group than that in the control group (45.7% vs. 82.9%, P<0.05). At 12 weeks after surgery, there were no significant differences in pain scores or hematoma proportions between the two groups. The TCM symptom scores were lower in the observation group than those of the control group at 4 weeks and 12 weeks after operation (P<0.05). Conclusion Hongjin Xiaojie capsule can promote the absorption of hematoma after Mammotome surgery, effectively alleviate breast hematoma and pain, and have high safety, demonstrating broad clinical application value.

Key words: breast, hematoma, minimally invasive surgical procedures, Hongjin Xiaojie capsules, absorption and dispersion of blood stasis

中图分类号:

R271.44，R655.82

图/表 5

表1 Comparison of general clinical data between the two groups

Tab.1 2组患者一般资料比较（n=35）

组别	年龄/岁	肿块数目/个	肿块长径/mm	手术时长/min
对照组	33.06±8.35	3（2，4）	17（13，23）	14（10，27）
观察组	33.46±9.79	3（2，4）	15（13，22）	20（14，30）
t或Z	0.184	0.372	0.825	1.353

图1 患者术后72 h、4周、12周彩色超声图 A：麦默通微创旋切手术后72 h血肿形成，可见边界不规则混合回声团块；B：术后4周可见皮下长条状不规则低回声区；C：术后12周血肿完全吸收，未见明显异常回声团块。

Fig.1 Color ultrasound image of a patient 72 hours, 4 weeks and 12 weeks after surgery

表2 Comparison of postoperative pain VAS scores between the two groups of patients

Tab.2 2组患者术后疼痛VAS评分比较（分）

组别	n	术后72 h	术后4周	术后12周
对照组	35	4.06±1.45	3（2，4）	1（0，1）
观察组	35	4.14±1.56	2（1，3）^a	1（0，1）
t或Z		0.238	3.824^＊	1.062

表3 Comparison of postoperative hematoma occurrence between the two groups of patients

Tab.3 2组患者术后血肿发生情况比较 [例（%）]

组别	n	术后4周	术后12周
对照组	35	29（82.9）	6（17.1）
观察组	35	16（45.7）	5（14.3）
χ²		10.516^＊	0.108

表4 Comparison of traditional Chinese medicine syndrome scores between the two groups of patients

Tab.4 2组患者中医症候积分比较（分）

组别	n	术后72 h	术后4周	术后12周
对照组	35	11.54±0.47	7.77±2.41	2（2，4）
观察组	35	10.86±0.42	6.00±2.52	2（0，2）
t或Z		0.958	2.753^＊	2.391^＊

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红金消结胶囊治疗麦默通微创旋切术后血肿的临床观察

Clinical observation of HongjinXiaojie capsule in the treatment of hematomas after minimally invasive vacuum-assisted Mammotome mastectomy

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