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子宫、卵巢不同术式对围绝经期妇女生活质量的影响

吴璠1,尹利荣2,郭素杰1,王芳1,陈逢振1   

  1. 1. 天津医科大学第二医院
    2. 天津医科大学第二医院妇科
  • 收稿日期:2011-08-01 修回日期:2011-11-27 出版日期:2012-07-15 发布日期:2012-07-15
  • 通讯作者: 尹利荣

Study on quality of life for perimenopausal women after different operations of uterus and ovary

  • Received:2011-08-01 Revised:2011-11-27 Published:2012-07-15 Online:2012-07-15
  • Contact: Li-Rong YIN

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摘要： 摘要 目的：探讨围绝经期妇女子宫切除同时是否保留卵巢对其生活质量的影响。方法：将因子宫或卵巢良性疾病而行手术的围绝经期妇女分为3组。A组(40例)：子宫切除术+双附件切除；B组(20例)：子宫切除术+一侧附件切除；C组（40例）：子宫切除术。分别在术前及术后2个月、6个月测定血FSH、LH、E2水平，并在术后2个月、6个月对手术后患者进行随访。结果：A组与B组相比，体内激素水平有统计学意义（P<0.05）,A组围绝经期症状较明显；A组与C组相比，体内激素水平有显著变化，有统计学意义（P<0.05）,A组的围绝经期症状明显；B组与C组相比，术后2个月激素水平下降有差异，术后6个月无差异。围绝经期症状表现无统计学意义（P>0.05）。结论：围绝经期妇女行子宫切除术时同时切除卵巢会出现较明显绝经期综合症，保留卵巢，延缓激素水平下降，推迟绝经期综合症的出现，提高妇女生活质量。

关键词: 子宫切除术, 卵巢切除术, FSH, LH, E2

Abstract: Abstract：Objective:To investigate the influence on quality of life for perimenopausal women whether reservation of ovary on the hysterectomy．Methods:Perimenopausal women with uterine or ovarian surgery for benign disease are divided into 3 groups.group A（40 cases）: hysterectomy plus bilateral adnexectomy;group B（20 cases）: hysterectomy plus ani-lateral adnexectomy;group C(40 cases): simple hysterectomy..The levels of FSH、LH、E2 were measured before operation and 2,6months after operation,and the symptoms of peri-menopausal period was observed in 2，6 months after the operation.Results:Blood hormones of group A were significantly differential compared with the group B（P<0.05）,and more symptoms of prei-menopausal period.Blood hormones of group A were more significantly differential compared with the group C（P<0.05）, and most symptoms of prei-menopausal period.Two months after operation decline in hormone levels of group B were significantly differential compared with the group C,but no significantly differential in 6 months after operation .No differences of symptoms of peri-menopausal period were observed between groups（P>0.05）. Conclusion:Ovary removal in hysterectomy will appear more menopausal syndrome, so ovaries should be preserved and slow decline in hormone levels to delay the emergerce of menopausal syndrome and improve the quality of life of women.

Key words: Hysterectomy, Ovariotomy, FSH, LH, E2