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磁共振弥散加权成像对脑梗死的诊断价值

孙静   

  1. 西安医学院医学技术系
  • 收稿日期:2011-08-11 修回日期:2011-09-05 出版日期:2011-11-15 发布日期:2011-11-15
  • 通讯作者: 孙静

The diagnostic value of DWI in diagnosis of ischemic brain lesions

  • Received:2011-08-11 Revised:2011-09-05 Published:2011-11-15 Online:2011-11-15

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摘要： 摘 要：目的 探讨弥散加权成像（DWI）及表观弥散系数（ADC）值对脑梗死的诊断价值。 方法 对78例缺血性脑梗死病例根据发病时间进行分组，均完成常规MR检查T1WI、T2WI扫描以及DWI检查，在病变部位绘制ROI并通过软件计算ADC值。 结果 超急性期缺血性脑梗死病灶常规MRI检查未见异常，而DWI呈高信号，平均ADC值下降为0.512±0.07×10－3mm2/s，低于正常脑组织；急性期DWI呈高信号，平均ADC值下降至最低为0.423±0.13×10－3mm2/s；亚急性期DWI呈低信号，平均ADC值上升为0.781±0.05×10－3mm2/s，接近正常脑组织；慢性期DWI呈明显低信号，平均ADC值升高为3.238±0.35×10－3mm2/s，明显高于脑组织接近脑脊液。 结论 DWI能够有效显示超急性期和急性期的缺血性脑梗死病灶，结合ADC值变化规律不仅可用于诊断，还可以用于判断病程发展时期。

关键词: 弥散加权成像, 表观弥散系数, 脑梗死

Abstract: Abstract: Objective To explore the diffusion-weighted imaging (DWI) and apparent dispersion coefficient (ADC) value on the diagnostic value of brain ischemic infarction. Methods 78 cases of ischemic cerebral infarction cases according to the time, all groups doing MR T1WI, T2WI scan and DWI check, drawing ROI in the lesion and calculate ADC values through the software. Results The ischemic cerebral infarction lesions of hyperacute phase on conventional MRI examination showed no abnormalities, and DWI showed high signal, the average ADC values decreased to 0.512±0.07×10－3mm2/s, lower than that of normal brain tissue. The lesions of acute phase DWI showed high signal, the average ADC values decreased to a minimum of 0.423 ±0.13 ×10－3mm2/s. The lesions of subacute stage DWI showed low signal, average ADC values increased to 0.781±0.05×10－3mm2/s, close to the normal brain tissue. The lesions of chronic phase DWI showed obviously low signal, the average ADC values increased to 3.238±0.35×10－3mm2/s, was significantly higher than the brain tissue close to the cerebrospinal fluid. Conclusion DWI can effectively shows the hyperacute phase and the acute phase of ischemic cerebral infarction lesions, not only can be used for diagnosis, can also be used for the difference between the new and the old infarction, judge development period of disease.

Key words: diffusion-weighted imaging, apparent diffusion coefficient, ischemic infarction