天津医药

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高血压患者发生心血管事件的危险因素分析

屈志萍1,刘新民2,张燕杰3,李晓卫3   

  1. 1. 天津医科大学公共卫生学院；天津市胸科医院
    2. 天津医科大学
    3. 天津市胸科医院
  • 收稿日期:2010-05-13 修回日期:2010-08-20 出版日期:2011-01-15 发布日期:2011-01-15
  • 通讯作者: 张燕杰

Patients with hypertension risk factors of cardiovascular events

  • Received:2010-05-13 Revised:2010-08-20 Published:2011-01-15 Online:2011-01-15

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摘要： 目的：探讨高血压患者发生心血管事件的相关危险因素。方法：选取我院患有高血压的住院患者507例，收集全部病历资料，对发生心血管事件与未发生心血管事件患者的各项指标进行分析，对相关因素进行Logistic回归分析，探讨影响心血管事件的危险因素。结果：心血管事件的发生率为46.15%（234/507），其中男70.09％（164/234），女29.91％（70/234）。发生心血管事件的危险因素包括年龄、性别、体质指数（BMI）、低密度脂蛋白胆固醇C（LDL-C）及血浆纤维蛋白原。结论：对于高血压患者，除性别、年龄、体质指数和LDL-C这些传统的心血管事件危险因素外，血浆纤维蛋白原也是较为独特的危险因素，应引起足够重视。

关键词: 高血压, 心血管疾病, 危险因素, Logistic模型, 人体质量指数, 纤维蛋白原

Abstract: Objective: To explore the related risk factors of cardiovascular events in patients with hypertension. Methods: Clinical data from 507 patients with hypertension who hospitalized in Tianjin Chest Hospital from Jan 2007 to Dec 2009 were analyzed focusing on the risk factors of cardiovascular events. We analyze the indicators between patients who occurred with and without cardiovascular events. We used Logistic regression to analyze the related factors in order to explore the risk factors of cardiovascular events. Results: Among the 507 patients with hypertension, 288 were male and 219 were female. The incidence of cardiovascular events is 46.15%. The incidence is 70.09% in male and 29.91% in female. The independent risk factors of cardiovascular events were age, sex, BMI, LDL-C and fibrinogen. Conclusions: For patients with hypertension, fibrinogen is another independent risk factor for cardiovascular events besides traditional risk factors. We should pay more attention to it.

Key words: hypertension, cardiovascular diseases, risk factors, Logistic Models, body mass index, fibrinogen