天津医药 ›› 2016, Vol. 44 ›› Issue (12): 1456-1459.doi: 10.11958/20160626

• 临床研究 • 上一篇    下一篇

天津市和平区成年人内脏型肥胖与高尿酸血症的关系

郑莉1 , 张美琳1 , 李萍1 , 朱玉凤1 , 常红1,2 , 黄国伟1△   

  1. 1 天津医科大学公共卫生学院营养与食品卫生学系 (邮编 300070); 2 天津医科大学康复与运动学系
  • 收稿日期:2016-07-06 修回日期:2016-09-25 出版日期:2016-12-15 发布日期:2017-01-26
  • 通讯作者: 黄国伟 △通讯作者 E-mail: huangguowei@tmu.edu.cn E-mail:972675559@qq.com
  • 作者简介:郑莉 (1990), 女, 硕士在读, 主要从事营养与慢性病的防治研究
  • 基金资助:
    国家科技支撑计划项目 (2012BAI02B00)

The relationship between visceral obesity and hyperuricemia in adults of Heping District of Tianjin

ZHENG Li 1 , ZHANG Meilin1 , LI Ping1 , ZHU Yufeng1 , CHANG Hong1,2 , HUANG Guowei 1△   

  1. 1 Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China; 2 Department of Rehabilitation and Sports Medicine, Tianjin Medical University
  • Received:2016-07-06 Revised:2016-09-25 Published:2016-12-15 Online:2017-01-26
  • Contact: HUANG Guowei △Corresponding Author E-mail: huangguowei@tmu.edu.cn E-mail:972675559@qq.com

摘要: 摘要: 目的 分析内脏型肥胖与高尿酸血症 (HUA) 的关系, 为进一步研究肥胖和 HUA 的关系提供依据。方法选取 2014 年在天津市和平区健康教育指导中心进行健康体检的 1 824 例体检人员作为研究对象, 对所有研究对象进行体格检查和生化指标检查, 并测量内脏脂肪面积 (VFA)。采用 Logistic 回归分析内脏型肥胖与 HUA 之间的关系。结果 随着 VFA 的增大, 男、 女性 HUA 的患病率呈上升趋势 (P<0.05); 且 VFA、 腰围 (WC) 和腰臀比 (WHR) 与血尿酸 (SUA) 水平均呈正相关 (P<0.05)。Logistic 多因素回归分析显示, 男性 VFA (OR=1.805, 95%CI=1.166~ 2.794) 和 WHR (OR=2.108, 95%CI=1.061~4.189) 是 HUA 发生的影响因素; 女性 VFA (OR=1.775, 95%CI=1.154~ 2.732), WC (OR=2.015, 95%CI=1.137~3.570) 和 WHR (OR=2.489, 95%CI=1.400~4.426) 均是 HUA 发生的影响因素。结论 内脏脂肪的蓄积会增加 HUA 的发生风险。加强人群内脏型肥胖的检测对于预防 HUA 的发生具有重要意义。

关键词: 高尿酸血症, 内脏型肥胖, 内脏脂肪面积, 腰围, 腰臀比

Abstract: Abstract: Objective To analyze the relationship between visceral obesity and hyperuricemia (HUA), and to provide the basis for the further study of obesity and HUA. Methods A total of 1 824 participants came from Tianjin Heping District Health Education Guidance Center in 2014 were selected in this study. The investigation was performed with physical examination and laboratory test for all subjects. Body fat analyzer was used to measure the visceral fat area (VFA). The Logistic regression analysis was used to evaluate the relationship between visceral obesity and HUA. Results The prevalence of HUA in men and women increased gradually with VFA increasing (P<0.05). There was a positive correlation between VFA, waist circumference (WC), waist-to-hip ratio (WHR) and serum uric acid (SUA) level (P<0.05). According to the results of Logistic regression analysis, VFA (OR=1.805, 95%CI=1.166-2.794) and WHR (OR=2.108, 95%CI=1.061- 4.189) were the risk factors of HUA in men. And in women, VFA (OR=1.775, 95%CI=1.154-2.732), WC (OR=2.015, 95% CI=1.137- 3.570) and WHR (OR=2.489, 95% CI=1.400- 4.426) were the risk factors of HUA. Conclusion The accumulation of visceral fat will increase the risk of HUA. So it is necessary to strengthen the detection of visceral obesity to prevent the development of HUA.

Key words: hyperuricemia, visceral obesity, visceral fat area, waist circumference, waist-to-hip ratio