天津医药

天津医药 ›› 2017, Vol. 45 ›› Issue (1): 91-94.doi: 10.11958/20161044

• 诊断技术 • 上一篇    下一篇

超声造影对乳腺癌肝转移小结节的诊断价值

梁永平 1， 刘景萍 1， 王海霞 1， 张娟 2△， 胡建 1， 宋倩 1， 冯华梅 1   

  1. 1 唐山市人民医院超声科 （邮编 063000）， 2 乳腺外科
  • 收稿日期:2016-09-26 修回日期:2016-11-09 出版日期:2017-01-15 发布日期:2017-01-15

The diagnostic value of contrast-enhanced ultrasound in detecting small liver metastasis from breast cancer

LIANG Yong-ping1, LIU Jing-ping1, WANG Hai-xia1, ZHANG Juan2△, HU Jian1, SONG Qian1, FENG Hua-mei1   

  1. 1 Department of Ultrasonography, 2 Department of Breast Surgery， Tangshan People’ s Hospital, Tangshan 063000, China
  • Received:2016-09-26 Revised:2016-11-09 Published:2017-01-15 Online:2017-01-15

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摘要： 摘要： 目的 探讨超声造影（CEUS）在乳腺癌微小肝转移中的诊断价值。方法 选取 2015 年 7 月—2016 年 7 月在我院手术病理确诊为乳腺癌后常规超声检查怀疑肝转移的女性患者 92 例为研究对象， 每例研究对象选取 1 个 肝病灶进行 CEUS 检查。以穿刺病理结果为 “金标准” ， 以良、 恶性符合率比较 CEUS 与穿刺病理的一致性。结果 在 92 例常规超声诊断疑似乳腺癌肝转移者中， 病理确诊为良性者 54 例， CEUS 均诊断为良性， 病理确诊为转移者 38 例， CEUS 诊断正确 36 例。CEUS 对乳腺癌肝转移诊断的敏感度为 94.74%（36/38）、 特异度为 100%（54/54）、 阳性预 测值为 100% （36/36）、 阴性预测值为 96.43% （54/56）。结论 CEUS 对乳腺癌微小肝转移灶有较高的诊断效能， 具有 临床实用价值。

关键词: 超声检查, 乳腺肿瘤, 肿瘤转移, 声学造影

Abstract:

Abstract: Objective To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) in detecting small liver
metastasis (SLM) from breast cancer. Methods A total of 92 cases diagnosed as breast cancer by surgical pathology and
suspected SLM by conventional ultrasonography were included in this study. CEUS was used to check liver lesion in
patients. The biopsy operation was used as the gold standard. The coincidence rate of benign and malignant pathology was
used to compare the consistency between CEUS and biopsy pathology. Results In 92 cases suspected liver metastases of
breast cancer by routine ultrasound, there were 54 cases were diagnosed as benign by pathology, and all 92 cases were
diagnosed as benign by CEUS. Thirty- eight cases were diagnosed as metastasis by pathology, in which 36 cases were
correctly diagnosed by CEUS. The sensitivity of CEUS for the diagnosis of liver metastases of breast cancer was 94.74 % (36/
38), specificity was 100% (54/54), positive predictive value (PPV) was 100% (36/36) and negative predictive value (NPV) was
96.43% (54/56). Conclusion CEUS has a higher diagnostic value in SLM of breast cancer, and has clinical practical value.

Key words: ultrasonography, breast neoplasms, neoplasm metastasis, acoustic contrast