Abstract:  Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-hodgkin’ s lymphoma (NHL), which has a wide range in age of onset, and has obvious heterogeneity in clinical features, invasive areas, histomorphology, molecular genetics and immune phenotype. In addition, with the improvement of the diagnosis and treatment of malignant tumor, the report of multiple primary malignant tumors (MPMT) in the same patient is on the rise. This paper reports a case of DLBCL combined with thyroid neoplasms with paraplegia as the clinical manifestation.

Key words:  paraplegia, lymphoma, large B-cell, diffuse, primary lymphoma of bone, multiple primary malignant tumors