Tianjin Medical Journal

Tianjin Medical Journal ›› 2021, Vol. 49 ›› Issue (1): 103-106.doi: 10.11958/20201878

• Review • Previous Articles     Next Articles

Progress in the treatment of patent ductus arteriosus in preterm infants

ZHAO Ying1, TIAN Xiu-ying1, BIAN Xi-yun2△, ZHANG Wan-xian1   

  1. 1 Department of Neonatology, Tianjin Central Hospital of Gynecology and Obstetrics, Tianjin 300100, China; 2 Central Laboratory of Tianjin Fifth Central Hospital, Tianjin Key Laboratory of Epigenetics of Organ 
    Development of Premature Infants
  • Received:2020-07-03 Revised:2020-09-10 Published:2021-01-15 Online:2021-01-15

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Abstract: Abstract: Patent ductus arteriosus (PDA) is a disease that seriously affects the survival and quality of neonates, especially for premature infants. The treatment of PDA, however, is still controversial. This review introduces the research progress in the treatment of timing, methods (medical treatment, surgical ligation and preventive treatment) and drug selection (indomethacin, ibuprofen and paracetamol) of PDA in recent years, and analyzes their advantages and disadvantages.

Key words: ductus arteriosus, patent, indomethacin, ibuprofen, acetaminophen, ligation, infant, newborn, diseases