Abstract: Objective　To investigate the prevalence and management of perioperative pain in patients undergoing sacral tumor resection, and identify potential ways, in which pain management can be improved. Methods　The clinical data of 215 patients undergoing sacral tumor resection from January 2018 to December 2019 were collected. The main observation indicators included postoperative pain and postoperative opioid consumption, and secondary indicators included preoperative pain, analgesic regimes during and after surgery, length of hospital stay after surgery and surgery complications. Results　In 215 patients, there were 126 patients (58.6%) presented with chronic pain and forty nine patients (22.8%) required opioids preoperatively. Opioid-only analgesia was the mainstay of analgesia modality during and after surgery. On the first day after surgery, 112 patients (53.3%) suffered from moderate-severe pain. Postoperative pain severity was not associated with preoperative pain, tumor location or surgery procedures (P＞0.05). The postoperative opioid dosage was positively correlated with the pain severity (P＜0.05). By the 7 days after surgery, 42.3% of patients still required opioids,  and the proportion decreased to 26.0% by discharge. The length of hospital stay after surgery was positively related with postoperative pain severity (P＜0.05). Compared with patients who were not on preoperative opioids, patients on preoperative opioids required higher doses of opioids in the first 7 days after surgery (P＜0.05), and the proportion of patients required opioids 7 days after surgery and at discharge were increased (P＜0.05). Conclusion　Patients undergoing sacral tumor resection have a higher incidence of preoperative pain, severe postoperative pain and a large demand for opioids. It is necessary to further optimize the analgesia mode and improve the quality of postoperative analgesia management.

Key words: sacrum, bone neoplasm, pain management, pain, postoperative, analgesics, opioid, sacral tumor resection, multimodal analgesia