Abstract:

[Abstract] Objective To evaluate the clinical value of the regional wall motion in patients with suspected coronary artery disease by real-time three-dimensional echocardiography (RT-3DE) and two-dimensional speckle tracking imaging (2D-STI). Methods A total of 143 hospitaized patients with suspected coronary artery disease and normal wall motion de? tected by two-dimensional echocardiography (2DE) were enrolled and devided into group A (coronary stenosis ≥75%) 73 cases and group B (coronary stenosis < 75%) that include 70 cases according to coronary angiography results. Left ventricu? lar segmental ejection fraction (sEF) was measured by RT-3DE and peak systolic longitudial strain (SL) was measured by 2DSTI. ROC curves of the two measurements were generated and compared. Differences in sEF and SL between group A and group B were respectively analyzed. Results （1） Both sEF of RT-3DE and SL of 2D-STI in group A were significantly low? er than those in group B (P＜ 0.05);（2） sEF was positively correlated with SL(r=0.689， P＜ 0.05);（3） Compared with SL, sEF had larger area under ROC curve in some segments of left ventricle where both parameters are abnormal for the diagnosis of the coronary stenosis ≥75% (0.922 vs 0.874). Conclusion Regional wall motion of left ventricular can be measured by both RT-3DE and 2D-STI which can be both used to estimate the extend of stenosis of coronary artery. And RT-3DE is su? perior over 2D-STI.

Key words: real-time three dimensional echocardiography, two-dimensional speckle tracking imaging, coronary heart disease, regional wall motion