Abstract: Abstract Objective:Explore the implementation of standardized hospital perioperative period to prevent the feasibility and effectiveness of drugs for clinical rational drug use for reference. Methods:categories to choose surgical incision heart surgery cases in 2008to 120 cases of patients January to December as the program group, Use the medicine according to the norm project, 2007 to January-December as 117 cases of patients in the comparison group, according to the habits Drug method, timing of application of antibacterial drugs, Postoperative course of treatment,Postoperative infection rate, The average hospital stay on in areas such as statistical comparison. Results: Postoperative infection rate of the two groups, after changes in body temperature, The average hospital stay time was no significant difference (P> 0.05). Two groups of anti-bacterial drug administration time, the average after drug treatment significantly (P <0.05).Conclusion：ospital in the development and implementation of standardized perioperative drug prevention program is feasible, can be used as cardiac surgery antibiotics to prevent drug choice. At the same time facilitate the clinical rational drug use, thereby reducing the cost of health care, fundamentally improve the quality of medical services. Key words heart surgery Antibiotics Prevention of drug use Children's Author's address 300074 Tianjin Children's Hospital

Key words: Keywordsheart surgery, Antibiotics, Prevention of drug use, Children's