Abstract: Abstract Objective: To investigate the clinical effect of biteplate and interventional treatment of sodium hyaluronate on anterior disc displacement without reduction. Methods: Ninety-six patients with Anterior disc displacement without reduction were divided into three groups (32 patients in each group)，group A (biteplate treatment only), group B (interventional treatment only) and group C (combination of biteplate and interventional treatment). Three months after treatment，the pain index and maximal mouth opening were compared between groups. Results: After treatment, the maximal mouth opening was increased and the pain index was decreased in patients of three groups. The improvement was statistically significant (P<0.05 or P<0.01). The change of maximal mouth opening was bigger in combined group than that of biteplate treatment only and interventional treatment only group. The pain index was significantly lower in combined group and interventional treatment only group than that of biteplate treatment only group (P<0.001). Conclusions: The effect is obviously better in combination group than that of biteplate treatment only group and interventional treatment only group. The effect of sodium hyaluronate on alleviating pain is better than that of biteplate treatment.

Key words: dental occlusion temporomandibular joint dysfunction syndromehyaluronic acid injections, intra-articular biteplate