Abstract: Objective：To compare the differences of behavioural characteristics of human microsaccadic eye-movements between under normal refractive imaging state and optical imaging blur and to explore the the effect of abnormal visual experience on microsaccadic eye-movements. Methods：From January to March in 2011, 13 cases of subjects with corrected normal or normal vision were recruited from the outpatient clinic at Tianjin Eye Hospital.They were tested respectively under normal optical imaging state (group Nd for dorminant eyes and group Nn for non-dorminant eyes) and optical imaing blur state with -3.00D glass (group Bd for dorminant eyes and group Nn for non-dorminant eyes). A high-speed eye-movement recording system was used to monocularly record the fixational eye-movements of subjects'both eyes. A Matlab routine was used to detect and analyze the microsaccadic components of eye-movement waveforms. The microsaccadic amplitudes, peak velocities, occurrence rates, inter-microsaccadic intervals of all groups were analyzed and compared using Origin8.0 and Matlab2008 statistics toolbox. Results：There is no significant difference among mean microsaccadic amplitudes of all groups. The mean peak velocities of groups Bd and Bn was slower than groups Nd and Nn. The mean occurrence rates of groups Bd and Bn was less than groups Nd and Nn. The mean inter-microsaccadic intervals of groups Bd and Bn was longer than gorups Nd and Nn. There is no difference of peak velocity, occurrence rate and inter-microsaccadic interval under two imaging states betwwen dorminant eyes and non-dormiant eyes. Conclusion：High-speed eye-movement recording could provide useful assitance in evaluation of the visual quality and for exploring the relationship between visual perception and eye-movement behaviours.

Key words: ametropia, optical imaging blur, microsaccade, fixation, eye-movement