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The effect of different revascularization treatment on clinical outcomes in patients with coronary artery disease and type 2 diabetes

  

  • Received:2011-09-26 Revised:2011-11-11 Published:2012-06-15 Online:2012-06-15

Abstract: Abstract Objective:The study was performed to discuss the selection of different revascularization treatment in patients with coronary artery disease and type 2 diabetes. Methods:Four hundred and fifty-six patients with coronary artery disease and type 2 diabetes were divided into percutaneous coronary intervention(PCI)(n=288)and coronary artery bypass grafting(CABG)(n=168)group. The primary endpoints were major adverse cardiac events(MACE, including all-cause deaths, myocardial infarction,stroke)within 12 months,and the second endpoint was target vessel revascularization within 12 months. Results:The rate of myocardial re-infarction in PCI group was higher than CABG group(P=0.014)within 12 months. There were no significant differences between two groups in total adverse cardiac events(P=0.072)and other MACE(all P>0.05),also in target vessel revascularization(P=0.727)within 12 months. High-SYNTAX subgroup of PCI group had more incidence of adverse cardiac events than high-subgroup of CABG(P=0.017),while there is no difference in low-subgroup and middle-one(all P>0.05). Conclusions:It could not come to the conclusion that CABG was much better than PCI in patients with coronary artery disease and type 2 diabetes, but it might have lower incidence of adverse cardiac events in High-SYNTAX subgroup which patients accept CABG.

Key words: coronary artery disease diabetes mellitus, type 2 angioplasty, transluminal, percutaneous coronary coronary artery bypass, off-pump prognosis follow-up studies SYNTAX score, 非体外循环