Abstract:

[Abstract] Objective  To investigate the effects of mild hypothermia on the intracranial pressure (ICP), S-100B， blood glucose，mortality and the neural scores in patients with intracerebral hemorrhage (ICH) after stereotactic evacuation. Methods  The patients with ICH were randomly divided into control group (23 patients) and hypothermia group (24 patients) after operation. The treatment group accepted the mild hypothermia. In both group，the ICP was continuously measured in the first week. The S-100B and blood glucose were tested at the day of operation and 3，5 and 7- day after operation. The Neurological Deficit Scale Score was used to evaluate the neural function and mortality in patients at the day of operation and 2，4， 12，24，48-week after operation. Results  Compared with the control group，the values of ICP, S-100B and blood glucose were significantly reduced, and scale score was increased in treatment group. There was no significant difference in the mortal? ity between two groups (17.39% vs 20.83%).Conclusion  The mild hypothermia can assist to improve clinical outcome in patients with ICH after stereotactic evacuation，which is worth further clinical study.

Key words: Intracerebral hemorrhage, Stereotactic evacuation, Mild hypothermia, Intracranial pressure