Abstract: 【Abstract】 Objective To investigate the correlation between the number of biliary orifices and biliary complications, and to explore the preventive and curative methods for biliary complications. Methods Materials of 94 living donor liver transplantations were retrospectively analyzed. According to the various numbers of biliary orifices, we reviewed the incidence of biliary complications in all recipients. Results 63 grafts had one biliary orifice, 30 had two biliary orifices and 1 had three. Total incidence of biliary complications was 35.1%（33/94）, including bile leakage(6.4%) and biliary stricture(31.9%). The rate of biliary complication was significantly different between single biliary orifice group and multiple (P=0.02). Two patients suffering from bile leakage reoperated, four were cured through conservative treatment like drugs and bile drainage. 18 patients suffering from biliary anastomotic stoma stricture were cured through drugs, T-tube or ENBD drainage. The other ten patients were treated by bile drainage and placing stent through T-tube or endoscopic retrograde cholangioplasty. 1 non-anastomotic stoma stricture patient were treated by placing stent through T-tube. The other were cured through ENBD drainage. The liver function of all patients got better. Conclusion Under the premise of ensuring the safety of donors, harvesting single bile duct stump is considerable as far as possible, which can reduce biliary complication effectively. Bile drainage and radiate intervention treatment are effective for treatment of biliary complications.