Abstract: [Abstract] Objective To investigate the relationship between obstructive sleep apnea syndrome (OSAHS), SYNTAX（SX）score and coronary heart disease risk factors. Methods A total of 67 patients with OSAHS were divided into three groups included mild group (n=17), moderate group (n=16) and severe group (n=34) according to Chinese Society of Respiratory Diseases. The coronary angiography was performed and SXscore was measured in three groups. Results There were no significant differences in age, gender, weight, height, hypertension,and the proportion of smokers and diabetes between three groups (P＞0.05). There were also no significant differences in renal function, blood lipid, left ventricular diastolic diameter and left ventricular ejection fraction between three groups (P＞0.05). There was a significant difference in SXscore between three groups (P <0.01), and which increased with the elevated apnea hypopnea index (rs=0.326，P=0.007). Conclusion There is a positive correlation between the severity of OSAHS and serious and complex coronary artery lesions, which has partly guiding role for OSAHS patients with coronary heart disease taking revascularization therapy.

Key words: Obstructive sleep apnea hypopnea syndrome, Percutaneous transluminal coronary intervention, Coronary artery bypass grafting, SYNTAX Score