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Comparison of Efficacy of Three Methods to Deal with Hydrosalpinx before in vitro Fertilization and Embryo Transfer

LU Jing yuan,XU Wen jian   

  1. Department of Intervention, Nanjing Maternity and Child Health Hospital, Nanjing Medical University
  • Received:2014-04-09 Revised:2014-05-29 Published:2014-11-15 Online:2014-11-15
  • Contact: LU Jing yuan

Abstract:

[Abstract]   Objective   To compare three different curative effects on hydrosalpinx before in vitro fertilization and
embryo transfer (IVF-ET).   Methods   Patients receiving IVF-ET between January 2011 to December 2013 (n=731) due to tubal factor infertility (hydrosalpinx) were retrospectively analyzed. All patients were divided into four groups. Embolization group underwent fallopian tube embolization (n=257). Colostomy group underwent laparoscopic tubal umbrella end colosto?my (n=193). Excision group underwent laparoscopic tubal excision(n=198). Control group did not undergo any effusion before transplantation (n=83).   Results   Comparing main indicators of ovarian hyperstimulation (the number of antral follicles, the dosage of gonadotropin (Gn), the number of retrieved oocytes), indicators were better in embolism group, colostomy group and control group than those in excision group. Comparing main indexes of IVF-ET (embryo implantation rate, clinical pregnancy rate, abortion rate), indicators were better in embolism group, excision group than those in colostomy group while indi?cators in colostomy group were better than those in control group. The pregnancy rate in fallopian tube was the lowest in em?bolism group and excision group, and the highest in control group.   Conclusion   All three methods of processing hydrosal?pinx before transplantation ended with positive impact on IVF-ET, and fallopian tube embolization has certain advantages over the other two treatment measures.

Key words: fertilization in vitro, embryo transfer, hydrosalpinx, fallopian tube embolization, laparoscopic tubal um?brella end colostomy, laparoscopic tubal excision