Abstract: Co-infection of influenza A virus and other bacteria is one of the main causes of high pathogenicity and
mortality of influenza A. The common bacterial species co-infected with influenza A are staphylococcus aureus,
streptococcus pneumoniae and other bacteria. Clinicians are not well aware of it and are prone to misdiagnosis and wrong
treatment. This paper retrospectively analyzed the pathogenic characteristics, clinical manifestations, treatment and outcome of severe influenza with methicillin-resistant staphylococcus aureus (MRSA) sepsis in an 8-year-old girl hospitalized in our hospital, so as to improve the understanding of the disease. The recognition of severe influenza in children with bacteria infection is beneficial to early identification and improving the success rate of treatment.

Key words: methicillin-resistant staphylococcus aureus, sepsis, influenza A virus, respiratory insufficiency, child