Tianjin Medical Journal ›› 2025, Vol. 53 ›› Issue (12): 1326-1329.doi: 10.11958/20251282

• Multidisciplinary Diagnosis and Treatment • Previous Articles     Next Articles

Experience and clinical exploration by multidisciplinary diagnosis and treatment of cystic brain metastasis in a case of small cell lung cancer

YU Tao1(), WANG Junping2, ZHANG Rongxin3, LIU Bing4, XU Dongbo5, CHEN Yuan6, ZHONG Diansheng1,()   

  1. 1 Department of Oncology, Tianjin Medical University General Hospital, Tianjin 300052, China
    2 Department of Imaging, Tianjin Medical University General Hospital, Tianjin 300052, China
    3 Department of Radiation, Tianjin Medical University General Hospital, Tianjin 300052, China
    4 Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin 300052, China
    5 Department of Pathology, Tianjin Medical University General Hospital, Tianjin 300052, China
    6 Department of Thoracic Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China
  • Received:2025-04-01 Revised:2025-08-19 Published:2025-12-15 Online:2025-12-08
  • Contact: E-mail:zhongdsh@hotmail.com E-mail:yutaogh@tmu.edu.cn;zhongdsh@hotmail.com

Abstract:

With the continuous development of imaging techniques such as magnetic resonance imaging, the detection rate of brain metastases is increasing. Although the incidence rate of cystic brain metastasis is far lower than that of solid brain metastasis, patients with cystic brain metastasis are in urgent condition and have obvious space occupying effect, which is an urgent clinical problem. Previous literature has reported that cystic brain metastasis is more common in breast cancer and lung adenocarcinoma, especially in lung cancer patients with positive driver gene. This article reports a case of small cell lung cancer with cystic brain metastasis, which started with neurological symptoms, and was clinically cured under a multidisciplinary diagnosis and treatment model. Through dynamic imaging evaluation and molecular residual lesion detection, the patient can avoid overtreatment and achieved a relatively higher quality of life on the basis of prolonging survival.

Key words: small cell lung carcinoma, cystic brain metastases, multi-disciplinary treatment, molecular residual disease

CLC Number: