Abstract: Secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease (CKD).Physiologically，it is characterized by excessive synthesis and secretion of parathyroid hormone and excessive hyperplasia of parathyroid cells，causing multiple systemic diseases such as myocardium, skin，bone，hematopoietic system and lipid metabolism，which seriously affects the quality of CKD patients. This article summarizes the pathogenesis, surgical treatment and interventional treatment of SHPT in the literature at home and abroad. It aims to increase the understanding of secondary hyperparathyroidism in chronic kidney disease and improve the quality of life of patients with CKD, and to better complete the diagnosis and treatment of SHPT diseases.

Key words: kidney failure, chronic, hyperparathyroidism, secondary, parathyroidectomy, surgical procedures,operative, interventional therapyOperative, Interventional therapy