Abstract: Objective To compare the gestational weeks and pregnancy outcomes after selective laser coagulation of placental vessels (SLCPV) and selective radiofrequency ablation (RFA) in twin transfusion syndrome. Methods Eighty patients with twin transfusion syndrome admitted to our hospital from January 2015 to January 2018 were selected in this study. According to the surgical method, the patients were divided into SLCPV group and RFA group. SLCPV group was treated with SLCPV, and RFA group was treated with selective RFA fetal reduction. The gestational weeks, fetal status and pregnancy outcomes were observed in the two groups, and the therapeutic effects were compared between the two methods. Results The mean operation time was (28.74±4.59) min in SLCPV group, and which was significantly longer than that of RFA group (16.27 ± 3.94) min (P＜0.05). The incidence of maternal complications was 10.00% in SLCPV group, and no significant maternal complications were found in RFA group (P＞0.05). There were no significance in maternal complications between groups (P=0.116). The delivery rate was 90.00% (36/40) in SLCPV group and 100.00 (40/40) in RFA group (P＞0.05). The average gestational weeks of delivery were (30.15 ± 2.41) in SLCPV group, which were significantly shorter than those of RAF group (32.85±2.53, P＜0.05). There were no significant differences in the incidences of gestational diabetes mellitus (GDM) and pregnancy induced hypertension (HDCP) between the two groups (P＞0.05). There was no significant difference in the overall survival rate between the two groups (P＞0.05). The total survival rate of at least one fetus was 75.0% in SLCPV group, which was significantly lower than that of RFA group (P＜0.05). The body mass and Apgar score were significantly higher in RFA group than those in SLCPV group (P＜0.05). Conclusion SLCPV and selective RFA abortion can achieve better therapeutic effect for twin transfusion syndrome patients. However, RFA can better ensure the delivery and survival at least one fetus, and patients can obtain longer gestational weeks of delivery, which is a recommended treatment option.

Key words: twin transfusion syndrome, SLCPV, selective RFA reduction, week of pregnancy, pregnancy outcome