
Tianjin Medical Journal ›› 2026, Vol. 54 ›› Issue (6): 627-631.doi: 10.11958/20260225
• Clinical Research • Previous Articles Next Articles
ZHAO Likun1,2(
), CUI Shuangshuang1,2, YU Jingbo1,2, SUN Xiaolei3, ZHANG Wenhai4, MA Xinlong1,2,△(
)
Received:2026-01-20
Revised:2026-03-12
Published:2026-06-15
Online:2026-06-15
Contact:
△E-mail:maxinlong8686@sina.com
ZHAO Likun, CUI Shuangshuang, YU Jingbo, SUN Xiaolei, ZHANG Wenhai, MA Xinlong. The differences in bone mineral density and proximal femoral geometry between middle-aged and young adult patients with different types of hip fractures[J]. Tianjin Medical Journal, 2026, 54(6): 627-631.
CLC Number:
| 组别 | n | 年龄/岁 | 性别 (男/女) | BMI/ (kg/m2) | 损伤原因(低能量/高能量) |
|---|---|---|---|---|---|
| FNF组 | 77 | 41(35,48) | 59/18 | 22.97±3.26 | 58/19 |
| ITF组 | 55 | 42(36,46) | 54/1 | 24.58±3.96 | 32/23 |
| t、Z或χ2 | 0.088 | 12.101** | 2.559* | 4.346* |
Tab.1 Comparison of basic data between the two groups
| 组别 | n | 年龄/岁 | 性别 (男/女) | BMI/ (kg/m2) | 损伤原因(低能量/高能量) |
|---|---|---|---|---|---|
| FNF组 | 77 | 41(35,48) | 59/18 | 22.97±3.26 | 58/19 |
| ITF组 | 55 | 42(36,46) | 54/1 | 24.58±3.96 | 32/23 |
| t、Z或χ2 | 0.088 | 12.101** | 2.559* | 4.346* |
| 组别 | n | 年龄/岁 | 性别 (男/女) | BMI/ (kg/m2) | 损伤原因(低能量/高能量) |
|---|---|---|---|---|---|
| FNF组 | 55 | 41(34,48) | 54/1 | 23.59±3.32 | 38/17 |
| ITF组 | 55 | 42(36,46) | 54/1 | 24.58±3.96 | 32/23 |
| t、Z或χ2 | 0.081 | 1.000▲ | 1.550 | 1.414 |
Tab.2 Comparison of basic characteristics after PSM between the two groups
| 组别 | n | 年龄/岁 | 性别 (男/女) | BMI/ (kg/m2) | 损伤原因(低能量/高能量) |
|---|---|---|---|---|---|
| FNF组 | 55 | 41(34,48) | 54/1 | 23.59±3.32 | 38/17 |
| ITF组 | 55 | 42(36,46) | 54/1 | 24.58±3.96 | 32/23 |
| t、Z或χ2 | 0.081 | 1.000▲ | 1.550 | 1.414 |
| 组别 | n | BMD/(g/cm2) | 总体骨量 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 股骨颈 | Wards三角 | 大粗隆 | 全髋 | 正常 | 低骨量 | ||||||||
| FNF组 | 55 | 0.79±0.13 | 0.62±0.13 | 0.68±0.13 | 0.80(0.73,0.94) | 36 | 19 | ||||||
| ITF组 | 55 | 0.84±0.13 | 0.63±0.13 | 0.68±0.13 | 0.84(0.75,0.93) | 45 | 10 | ||||||
| t、Z或χ2 | 1.924 | 0.406 | 0.026 | 0.444 | 3.793 | ||||||||
| 组别 | 股骨近端几何参数 | ||||||||||||
| HAL/mm | NSA/° | BR | SM/mm3 | CSMI/mm4 | CSA/mm2 | ||||||||
| FNF组 | 116.78±6.56 | 128.56±2.92 | 8.30±2.45 | 622.07±150.04 | 12 780.20±3 284.69 | 138.76±25.26 | |||||||
| ITF组 | 117.27±6.65 | 129.40±4.17 | 7.82±2.74 | 703.76±176.60 | 14 419.13±4 191.75 | 149.42±27.07 | |||||||
| t | 0.465 | 1.200 | 1.011 | 2.705** | 2.382* | 2.244* | |||||||
Tab.3 Comparison of BMD and proximal femoral geometric parameters after PSM between the two groups
| 组别 | n | BMD/(g/cm2) | 总体骨量 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 股骨颈 | Wards三角 | 大粗隆 | 全髋 | 正常 | 低骨量 | ||||||||
| FNF组 | 55 | 0.79±0.13 | 0.62±0.13 | 0.68±0.13 | 0.80(0.73,0.94) | 36 | 19 | ||||||
| ITF组 | 55 | 0.84±0.13 | 0.63±0.13 | 0.68±0.13 | 0.84(0.75,0.93) | 45 | 10 | ||||||
| t、Z或χ2 | 1.924 | 0.406 | 0.026 | 0.444 | 3.793 | ||||||||
| 组别 | 股骨近端几何参数 | ||||||||||||
| HAL/mm | NSA/° | BR | SM/mm3 | CSMI/mm4 | CSA/mm2 | ||||||||
| FNF组 | 116.78±6.56 | 128.56±2.92 | 8.30±2.45 | 622.07±150.04 | 12 780.20±3 284.69 | 138.76±25.26 | |||||||
| ITF组 | 117.27±6.65 | 129.40±4.17 | 7.82±2.74 | 703.76±176.60 | 14 419.13±4 191.75 | 149.42±27.07 | |||||||
| t | 0.465 | 1.200 | 1.011 | 2.705** | 2.382* | 2.244* | |||||||
| [1] | 崔爽爽, 赵丽坤, 马信龙. 中国老年髋部骨折流行病学和疾病经济负担研究现状[J]. 中国中西医结合外科杂志, 2020, 26(3):567-570. |
| CUI S S, ZHAO L K, MA X L. Research status of epidemiological and economic burden on hip fractures in the elderly in China[J]. Chinese Journal of Integrated Traditional and Western Surgery, 2020, 26(3):567-570. doi:10.3969/j.issn.1007-6948.2021.03.034. | |
| [2] | 张明师, 盛学鑫, 艾合麦提江·艾尔肯, 等. 术前髋部骨折类型及严重程度与细胞因子及C反应蛋白的相关性研究[J]. 同济大学学报(医学版), 2024, 45(5):721-726. |
| ZHANG M S, SHENG X X, AIHEMAITIJIANG A, et al. Serum cytokines and CRP levels in different types and severity of hip fractures[J]. Journal of Tongji University(Medical Science), 2024, 45(5):721-726. doi:10.12289/j.issn.2097-4345.24187. | |
| [3] | 苏永彬, 王玲, 赵伟, 等. 老年女性低能量股骨颈骨折与转子间骨折的骨密度差异[J]. 中国骨与关节杂志, 2021, 10(3):235-240. |
| SU Y B, WANG L, ZHAO W, et al. Differences in bone mineral density of elderly female patients with low-energy femoral neck fracture and intertrochanteric fracture[J]. Chinese Journal of Bone and Joint, 2021, 10(3):235-240. doi:10.3969/j.issn.2095-252X.2021.03.013. | |
| [4] | SENRA A R, CARVALHO D R, SILVA M R, et al. Proximal femur geometry:a major predictor of proximal femur fracture subtypes[J]. Hip Int, 2023, 33(6):1100-1106. doi:10.1177/11207000221129785. |
| [5] | ZARZOUR F, AFTABI S, LESLIE W D. Effects of femoral neck width and hip axis length on incident hip fracture risk:a registry-based cohort study[J]. J Bone Miner Res, 2025, 40(3):332-338. doi:10.1093/jbmr/zjaf019. |
| [6] | ANDERSON K B, MOHEBBI M, TEMBO M C, et al. Hip structure and incident fracture:a time-updating survival analysis over 20 years of data from the Geelong Osteoporosis Study[J]. Arch Osteoporos, 2024, 19(1):110. doi:10.1007/s11657-024-01471-7. |
| [7] | MAEDA Y, SUGANO N, SAITO M, et al. Comparison of femoral morphology and bone mineral density between femoral neck fractures and trochanteric fractures[J]. Clin Orthop Relat Res, 2011, 469(3):884-889. doi:10.1007/s11999-010-1529-8. |
| [8] | CHA Y H, YOO J I. Comparison of hip structure analysis and grip strength between femoral neck and basicervical fractures[J]. BMC Musculoskeletal Disorders, 2021, 22(1):461. doi:10.1186/s12891-021-04363-w. |
| [9] | 中华医学会骨质疏松和骨矿盐疾病分会. 原发性骨质疏松症诊疗指南(2022)[J]. 中华骨质疏松和骨矿盐疾病杂志, 2022, 15(6):573-611. |
| Chinese Society of Osteoporosis and Bone Mineral Research. Guidelines for the diagnosis and treatment of primary osteoporosis(2022)[J]. Chin J Osteoporos Bone Miner Res, 2022, 15(6):573-611. doi:10.3969/j.issn.1674-2591.2022.06.001. | |
| [10] | 李兴国, 邓叶龙, 刘朝晖, 等. 中国老年髋部骨折流行病学特征分析[J]. 实用骨科杂志, 2021, 27(7):601-606. |
| LI X G, DENG Y L, LIU Z H, et al. The Epidemiology of hip fractures of the ederly in China[J]. Journal of Practical Orhopaedics, 2021, 27(7): 601-606. doi:1008-5572(2021)07-0601-06. | |
| [11] | 刘志伟, 叶欣, 高嘉琪, 等. 2009—2019年北京地区老年髋部骨折流行病学特点及年度变化趋势分析[J]. 北京医学, 2022, 44(6):494-498. |
| LIU Z W, YE X, GAO J Q, et al. Epidemiological characteristics and annual change trends of hip fractures in the elderly in some areas of Beijing from 2009 to 2019[J]. Beijing Med J, 2022, 44(6):494-498. doi:10.15932/j.0253-9713.2022.06.005. | |
| [12] | 刘刚, 杨明辉, 张京, 等. 北京地区老年髋部骨折的流行病学分布特点:多中心2 071例患者分析[J]. 中华创伤骨科杂志, 2022, 24(9):759-765. |
| LIU G, YANG M H, ZHANG J, et al. Epidemiological characteristics of geriatric hip fracture in Beijing:a multicenter analysis of 2 071 cases[J]. Chin J Orthop Trauma, 2022, 24(9):759-765. doi:10.3760/cma.j.cn115530-20220217-00099. | |
| [13] | 马仲锋, 冯国英, 齐明. 北京市东部地区髋部骨折发病特点及防治研究[J]. 中国骨质疏松杂志, 2020, 26(4):554-559. |
| MA Z F, FENG G Y, QI M. Study on the characteristic and prevention of hip fracture in eastern Beijing[J]. Chin J Osteoporos, 2020, 26(4):554-559. doi:10.3969/j.issn.1006-7108.2020.04.018. | |
| [14] | ALPANTAKI K, PAPADAKI C, RAPTIS K, et al. Gender and age differences in hip fracture types among elderly:a retrospective cohort study[J]. Maedica(Bucur), 2020, 15(2):185-190. doi:10.26574/maedica.2020.15.2.185. |
| [15] | ROTEM G, SHARFMAN Z T, RATH E, et al. Does hip morphology correlate with proximal femoral fracture type?[J]. Hip Int, 2020, 30(5):629-634. doi:10.1177/1120700019859275. |
| [16] | LI M, LV H C, LIU J H, et al. Differences in bone mineral density and hip geometry in trochanteric and cervical hip fractures in elderly Chinese patients[J]. Orthop Surg, 2019, 11(2):263-269. doi:10.1111/os.12456. |
| [17] | HU Z S, LIU X L, ZHANG Y Z. Comparison of proximal femoral geometry and risk factors between femoral neck fractures and femoral intertrochanteric fractures in an elderly Chinese population[J]. Chin Med J(Engl), 2018, 131(21):2524-2530. doi:10.4103/0366-6999.244118. |
| [18] | BOUXSEIN M L, ZYSSET P, GLÜER C C, et al. Perspectives on the non-invasive evaluation of femoral strength in the assessment of hip fracture risk[J]. Osteoporos Int, 2020, 31(3):393-408. doi:10.1007/s00198-019-05195-0. |
| [19] | ZHUANG H, LI Y, LIN J, et al. Cortical thickness in the intertrochanteric region may be relevant to hip fracture type[J]. BMC Musculoskelet Disord, 2017, 18(1):305. doi:10.1186/s12891-017-1669-z. |
| [20] | CHANG K P, CENTER J R, NGUYEN T V, et al. Incidence of hip and other osteoporotic fractures in elderly men and women:Dubbo osteoporosis epidemiology study[J]. J Bone Miner Res, 2004, 19(4):532-536. doi:10.1359/JBMR.040109. |
| [21] | CHEVALLEY T, GUILLEY E, HERRMANN F R, et al. Incidence of hip fracture over a 10-year period(1991-2000):reversal of a secular trend[J]. Bone, 2007, 40(5):1284-1289. doi:10.1016/j.bone.2006.12.063. |
| [22] | HANTOULY A T, ALBARAZANJI A, AI-JUBOORI M, et al. Epidemiology of proximal femur fractures in the young population of Qatar[J]. European Journal of Orthopaedic Surgery & Traumatology, 2024, 34(1):21-29. doi:10.1007/s00590-023-03664-1. |
| [23] | DEKEYSER G J, WILSON J M, KELLAM P J, et al. Young intertrochanteric femur fractures are associated with fewer complications than young femoral neck fractures[J]. J Orthop Trauma, 2021, 35(7):356-360. doi:10.1097/BOT.0000000000002005. |
| [24] | 刘泽民, 吕欣, 刘晋元, 等. 髋部骨折2342例流行病学分布特点的单中心分析[J]. 中国组织工程杂志, 2020, 24(32):5085-5091. |
| LIU Z M, LYU X, LIU J Y, et al. Epidemiological distribution characteristics of 2 342 cases of hip fracture: a single center analysis[J]. Chinese Journal of Tissue Engineering Research, 2020, 24(32):5085-5091. doi:10.3969/j.issn.2095-4344.2853. | |
| [25] | 赵丽坤, 崔爽爽, 马剑雄, 等. 成年股骨颈骨折临床特征分析:一项基于医院的回顾性研究[J]. 中华骨科杂志, 2021, 41(3):157-164. |
| ZHAO L K, CUI S S, MA J X, et al. Clinical characteristics analysis of adult femoral neck fracture:a retrospective hospital-based study[J]. Chin J Orthop, 2021, 41(3):157-164. doi:10.3760/cma.j.cn121113-20200425-00292. | |
| [26] | 李长洲, 庞炎旭, 于利, 等. 骨密度在髋部骨质疏松性骨折风险评估中的价值[J]. 中国骨质疏松杂志, 2020, 26(7):1023-1027. |
| LI C Z, PANG Y X, YU L, et al. The value of bone mineral density in assessing the risk of osteoporotic hip fractures[J]. Chin J Osteoporos, 2020, 26(7):1023-1027. doi:10.3969/j.issn.1006-7108.2020.07.017. | |
| [27] | MAZZA E, FERRO Y, PUJIA R, et al. Bending resistance at hip and fractures risk in postmenopausal women independent of bone mineral density[J]. J Clin Densitom, 2022, 25(2):198-207. doi:10.1016/j.jocd.2021.08.001. |
| [28] | JOHANNESDOTTIR F, POOLE K E, REEVE J, et al. Distribution of cortical bone in the femoral neck and hip fracture:a prospective case-control analysis of 143 incident hip fractures;the AGES-REYKJAVIK study[J]. Bone, 2011, 48(6):1268-1276. doi:10.1016/j.bone.2011.03.776. |
| [29] | KANAZAWA T, OHMORI T, TODA K, et al. Relationship between site-specific bone mineral density in the proximal femur and instability of proximal femoral fractures:a retrospective study[J]. Orthop Traumatol Surg Res, 2023, 109(5):103496. doi:10.1016/j.otsr.2022.103496. |
| [30] | NAKAMURA N, KYOU T, TAKAOKA K, et al. Bone mineral density in the proximal femur and hip fracture type in the elderly[J]. J Bone Miner Res, 1992, 7(7):755-759. doi:10.1002/jbmr.5650070705. |
| [31] | RATHBUN A M, MAGAZINER J, SHARDELL M D, et al. Differences in geometric strength at the contralateral hip between men with hip fracture and non-fractured comparators[J]. Bone, 2020, 132:115187. doi:10.1016/j.bone.2019.115187. |
| [32] | YAMAUCHI K, NAOFUMI M, SUMIDA H, et al. Comparison of morphological features in the femur between femoral neck fractures and femoral intertrochanteric fractures[J]. Surg Radiol Anat, 2016, 38(7):775-780. doi:10.1007/s00276-016-1626-9. |
| [33] | ZIA ZIABARI S M, JONI S S, FAGHANI M, et al. Comparative study of the neck shaft angle in femoral neck and intertrochanteric fractures in north part of Iran[J]. Int J Burns Trauma, 2020, 10(5):225-230. |
| [34] | VLACHOS C, AMPADIOTAKI M M, PAPAGRIGORAKIS E, et al. Distinctive geometrical traits of proximal femur fractures-original article and review of literature[J]. Medicina(Kaunas), 2023, 59(12):2131. doi:10.3390/medicina59122131. |
| [35] | JADZIC J, ZAGORAC S, DJURIC M, et al. Hip structure analysis and femoral osteodensitometry in aged postmenopausal women with hip osteoarthritis and femoral neck fracture[J]. Int Orthop, 2022, 46(12):2747-2755. doi:10.1007/s00264-022-05602-y. |
| [36] | 路迪迪, 张平, 刘盼, 等. 社区超重绝经后女性代谢综合征与骨转换指标、髋部骨几何参数的研究[J]. 中华内分泌代谢杂志, 2023, 39(6):479-485. |
| LU D D, ZHANG P, LIU P, et al. Bone turnover markers,hip bone geometry parameters and metabolic syndrome in community overweight postmenopausal women[J]. Chin J Endocrinol Metab, 2023, 39(6):479-485. doi:10.3760/cma.j.cn311282-20220613-00376. | |
| [37] | LI Y, LIN J, CAI S, et al. Influence of bone mineral density and hip geometry on the different types of hip fracture[J]. Bosn J Basic Med Sci, 2016, 16(1):35-38. doi:10.17305/bjbms.2016.638. |
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