Abstract: Abstract Objective：To investigate the safety and clinical effect of retroperitoneal laparoscopic partial nephrectomy(RLPN) for T1b renal cell carcinoma. Methods： Clinical data of 17(11 males，6 females，mean age 55（48～67）years) cases underwent RLPN for T1b renal cell carcinoma were analyzed retrospectively，and the mean tumor size was 5.3(4.3～6.8)cm. Surgical parameters(operation time，blood loss，warm ischemia time，postoperative stay time) and clinical outcomes were observed and analyzed. Results：Sixteen cases were completed successfully with only one case it converted to radical nephrectomy due to uncontrollable bleeding during operation. The average operation time was 125(105～175)min；the average warm ischemia time was 27(18～39)min；the average blood loss was 125(70～330)ml；the average postoperative stay time was 10(8～12)days. One patient had urine leakage and another had serum creatinine transient increase postoperation. All patients were very well recovered. Pathology indicated clear cell carcinoma in 14 cases，chromophobe carcinoma in 2 cases and papillary cell carcinoma in 1 case. During 4～112 months of following-up，all cases had normal renal function and had no recurrence of tumor，distant metastasis and transplant metastasis at Trocar wound. Conclusion：RLPN，which is safe and feasible，is one of operation choice for patients with T1b renal cell carcinoma，but its long-term effects still need large sample studies and long-term follow-up.

Key words: renal tumor, retroperitoneal laparoscopy, partial nephrectomy