Abstract: Objective:To compare outcomes of the diabetic and nondiabetic patients with coronary artery disease (CAD) undergoing successful percutaneous coronary intervention (PCI) ,and to investigate the relationship between type 2 diabetes mellitus(T2DM)and outcomes of CAD. Methods: The 1356 patients undergoing successful PCI in our hospital enrolled in the study, were separated into diabetic group (DM, n=292) and nondiabetic group (NDM, n=1064). Using the SYNTAX Score to evaluate the outcomes of CAG, then all the patients were divided into high, medium and low three groups. They had been followed up within 12 months. The clinical data were recorded including age, gender, history of hypertension, family history , the biochemical indicators including blood lipids, fibrinogen, and the echocardiography parameters. The endpoints were main adverse cardiovascular and cerebrovascular events (MACCE), including all-cause deaths, myocardial infarction (MI), target vessel revascularization (TVR) and stroke. All clinical date were statistically analyzed and processed. Results: Compared with the NDM group, the levels of FIB, uric acid in DM group was higher, while the mean left ventricular ejection fraction (LVEF) was lower. The mean SYNTAX score in DM group was higher than that in NDM (P<0.01); from the low group to the high group of SYNTAX score, the proportion of DM were gradually increased (P<0.01). During the follow-up the proportion of MI, death and total MACCE in DM were all significantly higher (all P<0.01). The proportion of TVR in DM was higher, and the proportion of stroke was slightly lower, while there were no difference in two groups (all P>0.05). Conclusions: The CHD patients with T2DM had a higher proportion of MACCE. It suggested that clinicians need to emphasize the control of blood glucose and blood lipid in the secondary prevention of the CHD patients.

Key words: coronary disease diabetes mellitus, type 2prognosis myocardial infarctionpercutaneous coronary intervention SYNTAX, SYNTAX